MRI: Acquisition of a GCMS to enhance undergraduate research training in the natural sciences at Virginia Wesleyan College

MRI：收购 GCMS 以加强弗吉尼亚卫斯理学院自然科学本科生研究培训

• 批准号: 1429247
• 负责人: Maury Howard
• 金额: $ 12.04万
• 依托单位: Virginia Wesleyan University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1429247&HistoricalAwards=false
• 关键词: MRI; Acquisition; GCMS; enhance; undergraduate

With this award from the Major Research Instrumentation program (MRI) and the Chemistry Research Instrumentation and Facilities program (CRIF), Virginia Wesleyan College will acquire a gas-chromatagraph and mass spectrometer analyzer (GC/MS). Gas chromatagraphy is a powerful technique employed to separate complex mixtures into individual components for further identification. This analysis will be performed in the mass spectometer where the separated components are injected for determination of their masses to aid characterization. The spectometer ionizes the components into a parent ion and smaller fragment ions and measures each of their masses. This highly sensitive technique allows detection and determination of the structure of the molecules in a complex mixture. The instrument will be used by undergraduate research students to advance their research projects and by students in laboratory courses using modern instrumentation. It will prepare them for technical careers and advanced educational opportunities. The proposal is aimed at enhancing research and education especially in areas such as (a) investigating the potential of natural products (specifically sea sponge toxins) for possible use in pharmaceuticals; (b) evaluating green chemistry practices for the development of pharmaceutical feedstocks; (c) evaluating and characterizing metal ion coordination materials for use as sensors; (d) evaluating the effectiveness of environmental pollution reduction measures; and (e) investigating plant evolution through the examination of the plant sterol pathway.

从主要研究仪器计划（MRI）和化学研究仪器和设施计划（CRIF）的这一奖项，弗吉尼亚卫斯理学院将获得气相色谱仪和质谱仪分析仪（GC/MS）。气相色谱法是一种强有力的技术，用于将复杂的混合物分离成单个组分，以便进一步鉴定。该分析将在质量流量计中进行，其中将分离的组分进样以测定其质量，以辅助表征。电子质量计将组分电离成母离子和较小的碎片离子，并测量它们的质量。这种高灵敏度的技术可以检测和确定复杂混合物中分子的结构。该仪器将用于本科研究生推进他们的研究项目和学生在实验室课程使用现代仪器。它将为他们的技术职业和先进的教育机会做好准备。该提案旨在加强研究和教育，特别是在以下领域：（a）调查天然产品的潜力，（特别是海绵毒素）用于药物的可能用途;（B）评价用于药物原料开发的绿色化学实践;（c）评价和表征用作传感器的金属离子配位材料;（d）评估减少环境污染措施的成效;及（e）透过研究植物固醇的途径，研究植物的进化。