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BIGDATA: F: DKA: CSD: Iterative Crowdsourced Hypothesis Generation

BIGDATA: F: DKA: CSD: Iterative Crowdsourced Hypothesis Generation
BIGDATA:F:DKA:CSD:迭代众包假设生成
批准号:
1447634
负责人:
James Bagrow
金额:
$59.99万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-09-15 至 2020-08-31

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英文摘要
Establishing causal relationships -- for example, that cigarette smoking causes lung cancer -- is one of the most challenging aspects of scientific research. Computers excel at calculation, but are unable to separate cause-and-effect from mere correlation. Humans, on the other hand, can make logical conclusions based on their experiences but, in the modern era of Big Data, there are far too many potential relationships for humans to manually examine. This research aims to build a crowdsourcing web platform to use the knowledge of interested non-experts (Hunch) and the algorithmic power of computers (Crunch) to discover and test causal relationships in large-scale data. Algorithms identify potential relationships and users are asked to validate them. Further, users are able to propose their own hypotheses that can subsequently be validated, creating an accelerating feedback loop of scientific discovery. The goal of systematically discovering causal relationships has the potential for broad societal impact, and virtually anyone with web access can participate directly in this scientific research.To support this goal, the researchers are developing novel statistical methods that determine the data types of crowd-suggested observables on the fly. For example, are 'wages' and 'gender' real-valued or binary variables? Finally, the crowd is a relatively limited resource. To use it efficiently, machine learning algorithms would identify which substructures in the correlational network are most likely to be causal, and then focus the crowd's efforts towards them. These efficient, adaptive methods allow causal relationships to be combined into larger chains that explain growing numbers of causes and effects.
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HIV-1逆转录酶/整合酶双重抑制剂DKA-DAPYs的分子设计、合成及抗HIV活性研究
  • 批准号:
    21402148
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    25.0万元
  • 批准年份:
    2014
  • 负责人:
    古双喜
  • 依托单位: