NSF/FDA SIR: Non-invasive assessment of neuromechanical outcomes from next generation peripheral nerve implants

NSF/FDA SIR：对下一代周围神经植入物的神经力学结果进行非侵入性评估

• 批准号: 1541908
• 负责人: Sameer Shah
• 金额: $ 12.72万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1541908&HistoricalAwards=false
• 关键词: NSF; FDA; SIR; Non; invasive

PI: Shah, Sameer Proposal Number: 1541908 The PI proposes to develop advanced evaluation criteria for peripheral nerve electrodes, which may alter nerve structure, biomechanics and physiological function, using non-invasive imaging modalities. Micro-CT and ultra short echo time MRI (UTE) will be used to study the structure-function effects of cuff electrodes (CEs) and Utah Slanted Electrode Arrays (USEAs) placed on the sciatic nerve between the hip and the knee (mid thigh) of rats. The training received by the graduate student and undergraduate student working on the project at the FDA will be excellent. Each research Objective describes experimental methods involved that would be appropriate for high school students as well as undergraduate and graduate students.

主要研究者：Shah，Sameer提案编号：1541908 PI提议使用非侵入性成像方式制定周围神经电极的高级评估标准，这可能会改变神经结构、生物力学和生理功能。将使用Micro-CT和超短回波时间MRI（UTE）研究袖带电极（CE）和犹他州倾斜电极阵列（USEA）对大鼠髋关节和膝关节（大腿中部）之间坐骨神经的结构-功能影响。在FDA从事该项目的研究生和本科生所接受的培训将非常出色。每个研究目标都描述了适用于高中生、本科生和研究生的实验方法。