Meeting: GO-FAANG, a Gathering on Functional Annotation of Animal Genomes, October 7-8, 2015, Washington DC

生物学正在从描述性科学过渡到预测性科学，在这种科学中，可以开发和测试特定基因组起点（基因型）的结果（表型）规则。生物学上的挑战是理解基因组中编码的指令，并预测由此产生的表型，即，“基因型到表型”的问题 一个名为“动物基因组功能注释”（FAANG）的新生项目已经在基层开发，拥有300多名成员，以启动驯养动物基因组的注释，并最终注释其他物种的基因组（www.faang.org），因为这些实验系统提供了解决基因型到表型问题的巨大潜力。该奖项部分支持一个研讨会，讨论FAANG倡议的协调。这次FAANG研讨会（GO-FAANG）将重点讨论小型和大型小组讨论，旨在制定政策和实用方法，以最大限度地提高动物基因组学这一关键下一阶段成功的可能性。 学术界和政府科学家在其职业生涯的各个阶段的参与将通过在小型和大型团体settings.A不同的发言人名单提供互动的各种机会鼓励已经开发，这将提供一个一瞥到动物功能基因组学中提供的令人难以置信的机会，以及对整合这样的愿景与FAANG项目的状态的观点。这一办法将明确FAANG取得成功的具体需要。社区讨论的重点将是实现FAANG的初步目标，其中包括：（a）确定研究工作的优先事项;（B）规划有效利用和分享样本、数据和计算工具所需的管理结构;（c）确定实现这些目标所需的资源。讲习班的成果将在同行评审的期刊上发表，并在粮农组织农业专家网网站上公布，供公众传播。

Biology is transitioning from a descriptive science to a predictive science, where rules for outcomes (phenotypes) given specific genomic starting points (genotypes) can be developed and tested. The biological challenge is to understand the instructions encoded in genomes and to predict the resulting phenotypes, i.e., the "genotype to phenotype" question. A nascent project named the Functional Annotation of ANimal Genomes (FAANG) with over 300 members has been developed at the grassroots level to initiate annotation of domesticated animal genomes and eventually the genomes of other species (www.faang.org) because these experimental systems offer great potential to address the genotype to phenotype question. This award partially supports a workshop to discuss the coordination of the FAANG initiative. This Gathering On FAANG (GO-FAANG) Workshop will have an emphasis on small and large group discussions designed to develop policies and practical approaches to maximize the probabilities of success of this crucial next phase in animal genomics. Participation of both academic and government scientists at various stages of their career will be encouraged by providing diverse opportunities for interaction in small and large group settings.A slate of diverse speakers has been developed that will provide a glimpse into the incredible opportunities available in animal functional genomics as well as a perspective on integrating such vision with the status of the FAANG project. This approach will provide clarity as to the specific needs for success of FAANG. Community discussions will be focused on accomplishing the initial goals of FAANG, which include (a) establishing priorities for research efforts; (b) planning the management structures required for efficient use and sharing of samples, data and computational tools; and (c) identifying resources needed to accomplish these goals. Outcomes from the workshop will be published in peer-reviewed journals and posted for public dissemination on the FAANG www-site.