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SBIR Phase I: Novel Industrially Viable Organometallic Catalyst Technologies

SBIR 第一阶段：新型工业可行的有机金属催化剂技术

基本信息

批准号：
1621126
负责人：
Anil Guram
金额：
$ 22.5万
依托单位：
Art of Elements, LLC
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-01 至 2017-09-30
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1621126&HistoricalAwards=false
关键词：
SBIR Phase Novel Industrially Viable

项目摘要

The broader impact/commercial potential of this Small Business Innovation Research Phase I project will be derived from the novel catalyst developed of the project. The project will, if successful, dramatically improve the efficiency and scope of a specific class of industrially significant chemical reactions which are indispensable for the manufacture of many useful products such as pharmaceuticals, agrochemicals, and electronics. The improvements, for example, will provide access to newer materials for the production of newer and improved related products to address unmet biological and engineering needs. The catalyst discoveries will also enhance the scientific knowledge base of both fundamental and applied catalysis science.The technical objectives in this Phase I research project are to develop a collection of novel and improved organometallic catalysts for industrially relevant cross-coupling reactions; and to address current unmet industrial needs for higher catalyst efficiency, selectivity and scope of these reactions. The Phase I research will involve detailed and innovative investigations of the current state-of-the-art catalysts; systematic and iterative design, synthesis, and testing of the new organometallic catalysts; and demonstration of improved performance of the new catalysts in relevant cross-coupling reactions. The catalysis knowledge gained from this Phase I research will enable catalyst design and development efforts in the current project for specific industrial applications. The development and commercialization of a collection of new and improved catalysts in this Phase I project will significantly expand the efficiency and industrial utility of cross- coupling reactions towards creating new products based on this chemistry.

这个小企业创新研究第一阶段项目的更广泛的影响/商业潜力将来自该项目开发的新型催化剂。如果成功，该项目将大大提高特定类别的工业重要化学反应的效率和范围，这些化学反应对于制造许多有用的产品（如药品，农用化学品和电子产品）是不可或缺的。例如，这些改进将为生产更新和改进的相关产品提供更新的材料，以满足未得到满足的生物和工程需求。催化剂的发现还将增强基础和应用催化科学的科学知识基础。该第一阶段研究项目的技术目标是开发一系列新型和改进的有机金属催化剂，用于工业相关的交叉偶联反应;并解决当前未满足的工业需求，以提高催化剂效率、选择性和这些反应的范围。第一阶段研究将涉及对当前最先进催化剂的详细和创新研究;新有机金属催化剂的系统和迭代设计，合成和测试;以及证明新催化剂在相关交叉偶联反应中的改进性能。从第一阶段研究中获得的催化知识将使当前项目中的催化剂设计和开发工作能够用于特定的工业应用。在该第一阶段项目中，一系列新的和改进的催化剂的开发和商业化将显著扩大交叉偶联反应的效率和工业实用性，以创造基于该化学的新产品。