Meeting: 7th Foundations of Systems Biology in Engineering Conference

该项目支持于2018年8月5-8日在伊利诺伊州芝加哥举行的第七届系统生物学工程基础国际会议(FOSBE)。NSF提供的资金用于补贴本科生和研究生的注册费用。系统生物学领域涉及对复杂的生物相互作用的整体研究，以努力了解有机体的功能。它已经成为分子和细胞生物学的简约主义方法和更全面地了解有机体的功能之间的桥梁，这是产生有用知识所必需的。例如，这些知识将应用于农业和医学。FOSBE会议召集了一个国际科学家小组，对系统生物学的当前最新水平进行了深入的审查和批判性评估，并讨论了该科学领域目前和未来的研究、教育和培训需求。会议还讨论了将科学知识转化为实际应用以造福社会，并确定了系统生物学领域的新方向、新机遇和新挑战。本次会议的计划包括平台演示，以及允许与会者自发互动的延长海报会议和集思广益会议。参加本科生和研究生以及博士后相关研究的学生有机会发表演讲，并加强他们在系统领域的培训。会议记录和结果将发表在适当的科学期刊上。系统生物学及其翻译科学对应的系统医学领域已成为简化论分子和细胞生物学方法与使用这些知识所需的系统水平理解之间的桥梁。系统方法借鉴了分子和细胞生物学中还原论方法的革命性进展，侧重于在整个有机体水平上组成个体和群体响应的基因、蛋白质和代谢物响应之间的关系。第七届工程系统生物学基础会议对当前的最先进技术进行了深入的审查和批判性评估，并讨论了研究、教育、培训和转化为实践的当前和未来需求。此外，还确定了系统生物学的新方向、新机遇和新挑战。本次会议由分子和细胞生物科学部的系统和合成生物学分部以及化学、生物工程、环境和运输系统分部的工程生物学和健康分部共同资助。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This project supports the 7th Foundations of Systems Biology in Engineering Conference (FOSBE), an international conference, being held in Chicago, Illinois, August 5-8, 2018. The funds provided by NSF are used to subsidize the cost of undergraduate and graduate student registration. The field of systems biology involves the holistic study of complex biological interactions in an effort to understand an organism's function. It has emerged as the bridge between the reductionist approaches of molecular and cellular biology and the more global understanding of an organism's function that is required in order to produce useful knowledge. Such knowledge would be applied to agriculture and medicine for example. The FOSBE conference convenes an international group of scientists that provides an in-depth review and critical assessment of the current state-of-the-art in systems biology and discusses the current and future needs of research, education and training for the scientific area. The conference also discusses the translation of scientific knowledge into practical applications for the benefit of society and identify new directions, opportunities and challenges in the area of systems biology. The program for this conference includes, platform presentations, as well as extended poster sessions and brainstorming sessions that allow attendees to spontaneously interact with each other. Attending undergraduate and graduate students and postdoctoral research associated have opportunities to give presentations and enhance their training in the area of systems. The conference proceedings and results will be published in an appropriate scientific journal.The field of systems biology, and its translational science counterpart systems medicine, has emerged as the bridge between reductionist molecular and cellular biology approaches and the systems-level understanding required to use this knowledge. Drawing upon the revolutionary advances from reductionist approaches in molecular and cellular biology, systems approaches focus on the relationships between the gene, protein, and metabolite responses that compose the individual and population responses at the whole organism level. The 7th Foundations of Systems Biology in Engineering Conference provides an in-depth review and critical assessment of the current state-of-the-art and discusses current and future needs of research, education, training and translation to practice. In addition, new directions, opportunities and challenges in systems biology are identified. The activities include poster sessions, a conference proceeding and brainstorming sessions.This conference is co-funded by the Systems and Synthetic Biology cluster in the Division of Molecular and Cellular Bioscience and the Engineering Biology and Health Cluster in the Division of Chemical, Bioengineering, Environmental and Transport Systems.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.