SBIR Phase I: New laparoscopic power morcellator with containment system for minimally invasive surgeries.

该SBIR一期项目的更广泛影响/商业潜力是促进腹部微创手术（MIS）新系统的开发。建议的手术将是一种更安全、更清洁、更有效的方法，通过小切口切除组织标本，如子宫肌瘤、子宫、肾脏或脾脏。现有的MIS方法和器械尚未优化，无法在不扩大切口或限制外科医生的可视化和可操作性的情况下从腔中移除分离组织。所提出的方法将使用新颖、更安全、更有效的仪器，通过MIS去除大型组织标本。拟议的项目将探索一种集成动力粉碎器和密封系统的翻译，用于从腔内切割和移除大型组织标本，而不会造成后续污染。拟进行的项目是使用标准MIS设备进行测试，包括5mm 30度角腹腔镜、腹腔镜摄像机、光源和监视器、CO2快速注入器。要切开的标本将是牛舌和土豆，这是子宫肌瘤的代表。建议的项目将为手术方案提供信息，以1)提高安全性和效率，2)防止被移除的组织污染腔体。模拟器和套管套将使用高精度ATP测试来评估组织污染的痕迹。该项目将探索与该过程相关的参数空间，包括功率粉碎器处于开启位置的最长时间、叶片温度和腔压力；以及对叶片和轴进行裂纹和疲劳断裂的事后检查；检查容器是否有磨损、刺穿和渗漏。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this SBIR Phase I project is to advance the development of a novel system for abdominal minimally invasive surgery (MIS). The proposed procedure will be a safer, cleaner, and more efficient method of removing tissue specimens, such as a uterine fibroid, uterus, kidney or spleen, through a small incision. Existing MIS methods and instruments are not yet optimized for the removal of the separated tissue from the cavity without enlarging an incision or limiting the surgeon's visualization and maneuverability. The proposed method will use novel, safer and more efficient instruments developed for the removal of large tissue specimens via MIS. The proposed project will explore translation of an integrated power morcellator and containment system for cutting and removing large tissue specimens from inside a cavity without subsequent contamination. The proposed project is to conduct tests with standard MIS equipment, including a 5mm 30 degree angled laparoscope, laparoscopic camera, light source and monitor, and a CO2 rapid insufflator. The specimens to be cut will be beef tongue and potato, which is representative of a fibroid uterus. The proposed project will inform a surgical protocol to 1) improve safety and efficiency, and 2) prevent cavity contamination by the removed tissue. The simulator and trocar sleeves will be evaluated for traces of tissue contamination using the highly-precise ATP test. The project will explore the parameter space associated with the procedure, including the maximum time the power morcellator is in the on position, blade temperatures, and cavity pressure; as well as post-procedure examinations of the blades and shaft for cracks and fatigue fractures; and of the containers for abrasions, punctures and leaks.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.