MRI: Acquisition of an Operando 500 MHz Nuclear Magnetic Resonance (NMR) Spectrometer

该奖项由主要研究仪器项目和化学研究仪器项目支持。威斯康星大学麦迪逊分校正在获取一台500 MHz核磁共振(核磁共振)光谱仪，该光谱仪配备了一个流管附件和专用软件，可以在实际实验条件下实时在线监测化学反应。该仪器支持威斯康星州高压反应堆(WiHP-N核磁共振)的Charles Fry教授和同事。这种光谱仪允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及允许研究具有生物相关性的物种。总体而言，核磁共振波谱是化学家用于阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。该仪器是该机构以及附近的麦迪逊学院、威斯康星大学拉克罗斯分校、威斯康星大学罗克郡分校、威斯康星大学白水分校、劳伦斯大学、马拉纳塔浸会大学、印第安纳州立大学和瓦尔帕莱索大学等学院本科生化学和生物化学教学和研究培训的组成部分。核磁共振设施通过与倡导科学、研究和教育对公众的重要性的部门项目密切合作，在加强大学和威斯康星州公民之间的关系方面发挥了重要作用。核磁共振光谱仪的获奖旨在加强各级的研究和教育。特别是对金属-金属键合催化剂的发现和碳氢功能化反应的影响。该仪器还用于探索光氧化还原催化、聚合物机械化学和三维(3D)打印。此外，它还提供了关于过渡金属催化反应的操纵性研究的信息。一种操作方法包括对正在进行反应的材料进行光谱表征，这与催化活性和选择性的测量相结合。该分光计还用于开发用于有氧氧化的催化剂。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. The University of Wisconsin Madison is acquiring a 500 MHz nuclear magnetic resonance (NMR) spectrometer equipped with a flow tube accessory and dedicated software that enable online monitoring of chemical reactions in real-time under actual experimental conditions. The instrumentation supports Professor Charles Fry and colleagues at the Wisconsin High-Pressure Reactor (WiHP-NNMR). This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as permitting study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at this institution and nearby colleges such as Madison College, University of Wisconsin La Crosse, University of Wisconsin Rock County, University of Wisconsin Whitewater, Lawrence University, Maranatha Baptist University, Indiana State University and Valparaiso University. The Magnetic Resonance Facility plays an important role in strengthening the relationship between the University and Wisconsin citizens by working closely with departmental programs advocating the importance of science, research, and education to the public.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts discovery of metal-metal bonded catalysts and carbon-hydrogen functionalization reactions. The instrumentation is also for exploring photoredox catalysis, polymer mechanochemistry and three-dimensional (3D) printing. In addition, it provides information on operando investigations of transition metal catalyzed reactions. An operando method involves spectroscopic characterization of materials undergoing reaction which is coupled simultaneously with measurement of catalytic activity and selectivity. The spectrometer is also used to develop catalysts for aerobic oxidation.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.