CAREER: Reconfiguring Life: Care and control in bioengineering

职业：重新配置生活：生物工程中的护理和控制

• 批准号: 2045925
• 负责人: Emma Frow
• 金额: $ 46.01万
• 依托单位: Arizona State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2045925&HistoricalAwards=false
• 关键词: CAREER; Reconfiguring; Life; Care; control

This proposal was funded in part by the Ethical and Responsible Research Program.There is growing interest in promoting responsible research and innovation around new biotechnologies, with the aim of fostering more socially robust and inclusive technologies. This CAREER project focuses specifically on the role of care in responsible innovation for bioengineering. It documents the growth and development of "biofoundries," a new type of facility for high-throughput design and genetic engineering being built in academic and industry settings. Biofoundries are working to make bioengineered molecules, materials and organisms for a wide range of research and industry sectors, and are positioning themselves as being able to make significant contributions to a more bio-based economy. This research uses qualitative and ethnographic methods to trace the "politics of care" in biofoundries at different scales: identifying the many ways care is manifest in the day-to-day practices of setting up and running a biofoundry, as well as the broader values guiding investment in and governance of biofoundries. These findings are being used to design and test tools to help biofoundry practitioners and undergraduate biomedical engineering students reconceptualize care and responsibility in more explicit and intentional ways. The long-term goal of these efforts is to help transform the culture of bioengineering education and practice towards more inclusive and sustainable outcomes.Using qualitative data collected through interviews, site visits and participant-observation, this project has three objectives: (1) to trace care practices in the building of high-throughput facilities for genetic engineering, (2) to examine the broader social and political contexts within which these facilities are being built, and how these are shaping visions of governance, and (3) to develop experimental tools and practices for re-shaping governance in and of biofoundries. This project builds on growing interest in practices and politics of care by science & technology studies (STS) scholars, in this case making connections with work on the governance of emerging technologies to advance theory and practice of governance. Research findings will generate a rich portrait of changing practices, relationships and accountabilities in a contemporary, high-stakes bioengineering venture. This project will deepen the methodological toolbox of existing responsible research & innovation initiatives, by developing interventions centered specifically around care. It also contributes to ongoing methodological discussions regarding the role of STS in engaging with and shaping emerging technologies.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该提案得到了道德和负责任研究方案的部分资助，人们对促进围绕新生物技术的负责任研究和创新越来越感兴趣，其目的是培育更具社会活力和包容性的技术。这个职业项目特别关注护理在生物工程负责任创新中的作用。它记录了“生物工厂”的成长和发展，这是一种在学术和工业环境中建造的高通量设计和基因工程的新型设施。Biofoundries正在努力为广泛的研究和工业部门制造生物工程分子，材料和生物体，并将自己定位为能够为更加生物化的经济做出重大贡献。本研究使用定性和人种学方法来追踪不同规模的生物制品中的“护理政治”：确定护理在建立和运行生物制品的日常实践中表现出来的多种方式，以及指导生物制品投资和治理的更广泛的价值观。这些发现被用于设计和测试工具，以帮助生物制药从业者和本科生物医学工程学生以更明确和有意识的方式重新定义护理和责任。这些努力的长期目标是帮助改变生物工程教育和实践的文化，使其取得更具包容性和可持续性的成果。该项目利用通过访谈、现场访问和参与者观察收集的定性数据，有三个目标：（1）追踪建造高通量遗传工程设施的护理做法，（2）研究这些设施正在建设的更广泛的社会和政治背景，以及这些背景如何塑造治理的愿景，以及（3）开发实验工具和实践，以重新塑造生物工厂的治理。该项目建立在科学技术研究（STS）学者对护理实践和政治日益增长的兴趣的基础上，在这种情况下，与新兴技术的治理工作建立联系，以推进治理的理论和实践。研究结果将在当代高风险的生物工程企业中产生丰富的不断变化的实践，关系和责任。该项目将深化现有的负责任的研究创新举措的方法工具箱，通过制定专门围绕护理的干预措施。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。