SBIR Phase I: Sustainable textile manufacturing through protein engineering

SBIR 第一阶段：通过蛋白质工程实现可持续纺织品制造

• 批准号: 2053091
• 负责人: Simardev Gulati
• 金额: $ 25.5万
• 依托单位: BARLEY & BRITCHES INC.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2053091&HistoricalAwards=false
• 关键词: SBIR; Phase; Sustainable; textile; manufacturing

The broader impact of this Small Business Innovation Research (SBIR) Phase I project will demonstrate the promise of transforming proteins found in agricultural waste into high-performance, cost-effective and environmentally friendly cotton, silk and polyester-like fibers. Textile production negatively impacts the environment and wastewater. Structural proteins found in agricultural waste are a substitute to natural silk, cotton, and theoretically polyester. The proposed project will advance a new, tough, cost-effective, environmentally friendly, protein-based textile fiber. The proposed textile will be both recyclable and biodegradable. Protein-based fibers will transform the $981 B global textile industry and enable new use of billions of pounds of agricultural waste. The proposed project will advance a technology to maintain protein primary structure (backbone chemistry) for synthetic textile development. The challenge is to simultaneously restore the protein secondary and tertiary structure responsible for the excellent balance of mechanical and aesthetic properties inherent in natural plant and animal sourced fibers. The proposed process integrates protein molecular biology with novel, ecologically sound fiber formation engineering. Advanced manufacturing will be used to recreate fibers in a closed-loop process recycling chemicals and water without harmful byproducts.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个小企业创新研究（SBIR）第一阶段项目的更广泛影响将展示将农业废物中发现的蛋白质转化为高性能、具有成本效益且环保的棉花、丝绸和聚酯类纤维的前景。 纺织生产对环境和废水产生负面影响。 在农业废料中发现的结构蛋白是天然丝、棉花和理论上聚酯的替代品。拟议的项目将推进一种新的，坚韧的，具有成本效益的，环保的，基于蛋白质的纺织纤维。拟议的纺织品将是可回收和可生物降解的。蛋白质纤维将改变价值981 B美元的全球纺织业，并使数十亿磅农业废物得到新的利用。 拟议的项目将推进一项技术，以保持蛋白质的一级结构（骨架化学），用于合成纺织品的开发。 挑战在于同时恢复蛋白质的二级和三级结构，这是天然植物和动物来源纤维固有的机械和美学特性的优异平衡。所提出的工艺将蛋白质分子生物学与新型的生态合理的纤维形成工程相结合。先进制造将用于在闭环过程中重新制造纤维，回收化学品和水，而不产生有害副产品。该奖项反映了NSF的法定使命，并且通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。