STTR Phase II: High-quality, Quick-apply Electroencephalography (EEG) for Improved Diagnosis of Brain Disorders

STTR 第二阶段：高质量、快速应用的脑电图 (EEG)，以改进脑部疾病的诊断

• 批准号: 2111735
• 负责人: Shawn Kelly
• 金额: $ 100万
• 依托单位: Precision Neuroscopics
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2024-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2111735&HistoricalAwards=false
• 关键词: STTR; Phase; II; quality; Quick

This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2).The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project will produce a high‐quality, easily‐applied cap for non‐invasively measuring brain signals from the scalp by electroencephalography (EEG). This cap will reduce the setup time for an EEG procedure from 30 minutes to less than 5 minutes. This reduction in setup time will speed up procedures and reduce demand on specialized EEG technicians. Many geographic regions have wait times for EEG appointments of 4‐6 weeks; This wait will be alleviated by faster procedures and higher throughput. Additionally, the EEG cap designed in this project will increase accessibility of EEG to rural communities that don’t often have regular access to these technicians. Economically, the hospitals and clinics that perform EEG can reduce cost per procedure by reducing demand for EEG rooms and technician time. This reduction in EEG procedure costs is a small step towards controlling and reducing overall healthcare costs. This Small Business Technology Transfer (STTR) Phase II project is developing EEG platforms that will be used to explore new brain diagnostic algorithms. The project is introducing a novel electrode material to EEG, specifically, a soft sponge‐like material that holds water for a longer time than typical sponges, yet conducts electricity when dry. This EEG system also uses miniature printed circuit boards to hold amplifiers near each electrode. These circuit boards can be reconfigured, removing electrodes over scalp regions of recent injury or surgery. More importantly, the EEG cap resulting from this project can be scaled up (simply by adding more electrodes) to explore very high‐density EEG and novel algorithms for better diagnosing brain injuries and diseases. In particular, this project will provide hardware that enables new ways of looking at epilepsy and traumatic brain injuries.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项全部或部分由2021年美国救援计划法案（公法117-2）资助。该小企业技术转让（STTR）第二阶段项目的更广泛影响/商业潜力将产生高质量，易于应用的帽子，用于通过脑电图（EEG）从头皮无创测量大脑信号。该上限将EEG程序的设置时间从30分钟缩短至5分钟以下。设置时间的减少将加快程序并减少对专业EEG技术人员的需求。许多地理区域的EEG预约等待时间为4 - 6周;更快的程序和更高的吞吐量将缓解这种等待。此外，该项目设计的脑电图帽将增加农村社区的脑电图的可及性，这些社区通常无法定期获得这些技术人员。从经济上讲，执行EEG的医院和诊所可以通过减少对EEG室和技术人员时间的需求来降低每个程序的成本。EEG程序成本的降低是控制和降低整体医疗保健成本的一小步。 这个小企业技术转让（STTR）第二阶段项目正在开发EEG平台，用于探索新的大脑诊断算法。该项目正在将一种新型电极材料引入EEG，具体来说，是一种柔软的海绵状材料，比典型的海绵能保持更长的时间，但在干燥时导电。该EEG系统还使用微型印刷电路板将放大器保持在每个电极附近。 这些电路板可以重新配置，移除最近受伤或手术的头皮区域上的电极。更重要的是，该项目产生的EEG帽可以扩大规模（只需添加更多电极），以探索非常高密度的EEG和新算法，从而更好地诊断脑损伤和疾病。特别是，该项目将提供硬件，以实现看待癫痫和创伤性脑损伤的新方法。该奖项反映了NSF的法定使命，并且通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。