MRI: Acquisition of an ABI 3500xL Genetic Analyzer for the WVU Genomics Core Facility

西弗吉尼亚大学(WVU)被授予用ABI 3500xL替换和升级现有的应用生物系统3130xL遗传分析仪，允许增强西弗吉尼亚大学基因组和生物信息学核心设施(WVU-GBCF)目前提供的服务。具体地说，这种替代将缩短周转时间，带来更高质量的产出，并创造多路复用的能力，所有这些都将加强正在进行的地方和区域研究和教学努力。作为西弗吉尼亚州的土地授予机构，西弗吉尼亚州立大学和西弗吉尼亚州立大学GBCF致力于在大学和全州范围内提供培训和支持。人们对一般基因组学相关的研究和课程有着浓厚的兴趣，因此，西弗吉尼亚大学-GBCF为来自西弗吉尼亚大学所有校区和大阿巴拉契亚地区的学生提供了许多尖端的动手教育和培训机会。具体地说，该设施为学生和教师提供培训、故障排除和服务，其中DNA测序和/或片段分析是本科实验室课程的一部分。此外，WVU-GBCF提供的能力和资源是许多本科生和研究生论文和学位论文项目的核心，范围从具有重要农学意义的农作物的基因组对气候变化的反应到阿片类药物和精神刺激剂滥用的遗传学，这些主题对西弗吉尼亚州和全国都至关重要。ABI 3500xL基因分析仪将确保提供教育和培训机会，培养一支多样化和合格的劳动力队伍，能够应对紧迫的环境、医疗和生态挑战。西弗吉尼亚大学拥有一个充满活力、多产和跨学科的研究社区，其基因研究工作来自不同学科，包括生物化学、植物生物学、进化与物种形成、生态学、野生动物保护、传染病、微生物学、气候变化、药理学和生理学。西弗吉尼亚大学基因组学和生物信息学核心设施(WVU-GBCF)提供的资源提供高质量、负担得起的高效DNA测序、片段分析和细胞系认证服务，这些服务对西弗吉尼亚大学的遗传和基因组相关工作的成功至关重要。此外，WVU-GBCF支持该地区和全州几所依赖DNA测序和咨询服务的大学。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

An award is made to West Virginia University (WVU) to replace and upgrade the existing Applied Biosystems 3130xL genetic analyzer with the ABI 3500xL, allowing enhancements to the current services provided by the WVU Genomics and Bioinformatics Core Facility (WVU-GBCF). Specifically, this replacement will improve turn-around time, result in higher quality output, and create the capacity for multiplexing, all of which will strengthen ongoing local and regional research and teaching efforts. As the state of West Virginia’s land grant institution, WVU and the WVU-GBCF are committed to providing training and support at both the university and statewide levels. There is strong interest in general genomics-related research and coursework, and as such, the WVU-GBCF provides numerous cutting-edge hands-on educational and training opportunities for students from all WVU campuses and the greater Appalachian region. Specifically, the facility provides training, troubleshooting, and services for students and instructors where DNA sequencing and/or fragment analysis is conducted as part of undergraduate laboratory courses. Moreover, the capabilities and resources provided by the WVU-GBCF are central to numerous undergraduate and graduate student thesis and dissertation projects ranging from the genomic responses to climate change in agronomically important crop plants to the genetics of opioid and psychostimulant abuse, topics of vital relevance for both West Virginia and the nation. The ABI 3500xL genetic analyzer will ensure the provision of educational and training opportunities in the development of a diverse and well-qualified workforce capable of confronting pressing environmental, medical, and ecological challenges.WVU is home to a vibrant, productive, and interdisciplinary research community, with genetic research efforts from a diverse set of disciplines including biochemistry, plant biology, evolution and speciation, ecology, wildlife conservation, infectious disease, microbiology, climate change, pharmacology, and physiology. The resources available at the WVU Genomics and Bioinformatics Core Facility (WVU-GBCF) provide the high-quality, affordable, and efficient DNA sequencing, fragment analysis, and cell-line authentication services that are crucial to the success of genetic and genomic-related efforts at WVU. Further, the WVU-GBCF supports several universities in the region and across the state that rely on DNA sequencing and consultation services.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.