I-Corps: Web-based Application for the Treatment of Polycystic Ovary Syndrome (PCOS)

I-Corps：用于治疗多囊卵巢综合症 (PCOS) 的网络应用程序

• 批准号: 2126195
• 负责人: Jennifer Phy
• 金额: $ 5万
• 依托单位: Texas Tech University Health Science Center
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-15 至 2022-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2126195&HistoricalAwards=false
• 关键词: Corps; Web; based; Application; Treatment

The broader impact/commercial potential of this I-Corps project is the development of a web-based application to help women manage Polycystic Ovary Syndrome (PCOS). PCOS is the most common endocrine disorder in women and leads to higher risk of obesity, heart disease, diabetes, infertility, and cancer. Women with PCOS are using on average 5 to 6 separate apps to manage their symptoms. Many of these apps are not based upon research. Women with PCOS note frustration, confusion and exhaustion trying to determine the right diet and the right way to manage their health problems. Many do not have access to a specialist or even a local health care provider with knowledge of PCOS. The goal is to educate women with PCOS about their unique nutritional and metabolic needs and to offer “one place” for women with PCOS to go for evidence-based advice from experts in this field.This I-Corps project is based on the development of a web-based application for the treatment of Polycystic Ovary Syndrome (PCOS). Research has shown that PCOS patients may control and mitigate their symptoms by managing their diet. The unique feature of this diet is that it is not based on counting caloric intakes, rather it is based on eliminating certain elements from the diet. The technology is based on a prospective clinical trial leading to an average weight loss of 19 pounds in 8 weeks without counting calories, carbs or fats. In addition, participants showed a 50% reduction in fasting insulin and a significant reduction in total testosterone as well. The goals of the proposed technology are to provide evidence-based education about PCOS directly to patients, and to relieve some of the burden on health care providers who care for these patients. The goal is to provide education and treatment based on 10 years of research conducted by nutritional and medical experts for the management of PCOS.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该 I-Corps 项目更广泛的影响/商业潜力是开发基于网络的应用程序，帮助女性管理多囊卵巢综合症 (PCOS)。多囊卵巢综合症是女性最常见的内分泌疾病，会导致肥胖、心脏病、糖尿病、不孕不育和癌症的风险增加。患有 PCOS 的女性平均使用 5 到 6 个单独的应用程序来管理她们的症状。其中许多应用程序并非基于研究。患有多囊卵巢综合症的女性在尝试确定正确的饮食和管理健康问题的正确方法时会感到沮丧、困惑和疲惫。许多人无法接触到专家，甚至无法接触到了解多囊卵巢综合症的当地医疗保健提供者。目标是教育患有 PCOS 的女性了解她们独特的营养和代谢需求，并为患有 PCOS 的女性提供“一个地方”来寻求该领域专家的循证建议。这个 I-Corps 项目基于开发用于治疗多囊卵巢综合症 (PCOS) 的基于网络的应用程序。 研究表明，多囊卵巢综合症患者可以通过管理饮食来控制和减轻症状。这种饮食的独特之处在于，它不是基于计算卡路里摄入量，而是基于从饮食中消除某些元素。该技术基于一项前瞻性临床试验，在不计算卡路里、碳水化合物或脂肪的情况下，8 周内平均体重减轻 19 磅。此外，参与者的空腹胰岛素水平降低了 50%，总睾酮水平也显着降低。拟议技术的目标是直接向患者提供有关 PCOS 的循证教育，并减轻照顾这些患者的医疗保健提供者的一些负担。 目标是根据营养和​​医学专家 10 年来针对 PCOS 管理进行的研究，提供教育和治疗。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。