RAPID: REU Site: A Virtual Research Experience in Macromolecular Structure and Function

RAPID:REU 网站:大分子结构和功能的虚拟研究体验

基本信息

  • 批准号:
    2133816
  • 负责人:
  • 金额:
    $ 5.8万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-06-15 至 2022-05-31
  • 项目状态:
    已结题

项目摘要

The COVID pandemic has caused closures of REU Sites in summer 2020. The situation continues this summer 2021 with some REU programs already posting cancellations. This RAPID proposal will mitigate the inadequate number of available opportunities for students. The University of Illinois at Chicago (UIC), located in Chicago, Illinois, will support the training of seven students for eight weeks during the summer of 2021. Research will be conducted online with faculty located in Chicago, Evanston (IL), and Dallas (TX). The students, who are from groups under-represented in science or from schools with limited research opportunities, will learn how research is conducted, and many will present the results of their work at scientific conferences. This program provides vital training, mentoring, and professional skills development to enable and encourage talented students to continue in degrees and careers in science, which is vital for the future of US science and the economy. Students will participate in full-time mentored research projects using state-of-the-art computer-based methods to advance our understanding of the structure and function of DNA, proteins and other macromolecules. Assessment of the program will be done through the online SALG URSSA tool. Students will be tracked after the program in order to determine their career paths. The scientific theme of the program is Macromolecular Structure and Function. Faculty mentors come from UIC Departments of Biology, Physics, and Bioengineering, the University of Chicago Biological Sciences Collegiate Division, the University of Texas Southwestern Medical Center Green Center for Systems Biology, and the Northwestern University Molecular Biosciences Department. The computer-based projects include elucidating protein functional sites, conformational changes involved in aggregation, cellular targeting signals, and mechanisms of nutrient uptake. Program components include professional skills training in ethical issues, responsible conduct of research, diversity and inclusion, science careers, and oral and written scientific communication. Participants will present their accomplishments at a Research Symposium. More information is available by visiting /bios.uic.edu/profiles/jeffery-constance-j/, or by contacting the PI (Prof. Jeffery, cjeffery@uic.edu).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
2019冠状病毒病大流行导致REU站点于2020年夏季关闭。这种情况将持续到2021年夏天,一些REU项目已经取消。这一快速发展的建议将缓解学生可用机会数量不足的问题。位于伊利诺伊州芝加哥市的伊利诺伊大学芝加哥分校(UIC)将在2021年夏季为七名学生提供为期八周的培训。研究将与位于芝加哥、埃文斯顿(伊利诺伊州)和达拉斯(得克萨斯州)的教师在线进行。这些学生来自科学界代表性不足的群体或来自研究机会有限的学校,他们将学习如何进行研究,许多人将在科学会议上展示他们的工作成果。该计划提供重要的培训、指导和专业技能发展,以使和鼓励有才华的学生继续攻读科学学位和职业,这对美国科学和经济的未来至关重要。学生将参加全职指导的研究项目,使用最先进的计算机为基础的方法,以提高我们对DNA,蛋白质和其他大分子的结构和功能的理解。该计划的评估将通过在线SALG URSSA工具进行。课程结束后,将对学生进行跟踪,以确定他们的职业道路。该计划的科学主题是大分子结构和功能。教师导师来自UIC生物系、物理系和生物工程系、芝加哥大学生物科学系、德克萨斯大学西南医学中心绿色系统生物学中心和西北大学分子生物科学系。以计算机为基础的项目包括阐明蛋白质功能位点,涉及聚集的构象变化,细胞靶向信号和营养摄取机制。项目内容包括伦理问题的专业技能培训,负责任的研究行为,多样性和包容性,科学事业,口头和书面科学交流。参与者将在研究研讨会上展示他们的成果。更多信息可访问/bios.uic.edu/profiles/jeffery-constance-j/,或联系PI (Jeffery教授,cjeffery@uic.edu)。该奖项反映了美国国家科学基金会的法定使命,并通过基金会的智力价值和更广泛的影响审查标准进行评估,认为值得支持。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Constance Jeffery其他文献

Enzymes, Moonlighting Enzymes, Pseudoenzymes: Similar in Sequence but Different in Function
  • DOI:
    10.1016/j.bpj.2020.11.1943
  • 发表时间:
    2021-02-12
  • 期刊:
  • 影响因子:
  • 作者:
    Constance Jeffery
  • 通讯作者:
    Constance Jeffery
P107 USING BIOINFORMATICS TO PRIORITIZE FOR BIOCHEMICAL AND BIOPHYSICAL ANALYSIS SNPS AND PROTEINS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE
  • DOI:
    10.1053/j.gastro.2019.01.172
  • 发表时间:
    2019-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Chang Chen;Constance Jeffery
  • 通讯作者:
    Constance Jeffery
Identifying Ligand Binding Sites of Proteins using Crystallographic Bfactors and Relative Pocket Sizes
  • DOI:
    10.1016/j.bpj.2019.11.442
  • 发表时间:
    2020-02-07
  • 期刊:
  • 影响因子:
  • 作者:
    Navya Shilpa Josyula;Constance Jeffery
  • 通讯作者:
    Constance Jeffery
Moonlighting Proteins Database
  • DOI:
    10.1016/j.bpj.2010.12.1944
  • 发表时间:
    2011-02-02
  • 期刊:
  • 影响因子:
  • 作者:
    Mathew Mani;Constance Jeffery
  • 通讯作者:
    Constance Jeffery
In Silico Analysis of Amino Acid Substitutions Resulting from SNPs Associated with Inflammatory Bowel Disease
  • DOI:
    10.1016/j.bpj.2018.11.3007
  • 发表时间:
    2019-02-15
  • 期刊:
  • 影响因子:
  • 作者:
    Constance Jeffery;Chang Chen
  • 通讯作者:
    Chang Chen

Constance Jeffery的其他文献

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{{ truncateString('Constance Jeffery', 18)}}的其他基金

MCA: Using Multiple Approaches for Understanding RNA Binding by Enzymes in Intermediary Metabolism
MCA:使用多种方法了解中间代谢中酶与 RNA 的结合
  • 批准号:
    2321442
  • 财政年份:
    2023
  • 资助金额:
    $ 5.8万
  • 项目类别:
    Standard Grant
SGER: Proteomics-level Structural Biology of Transmembrane Proteins
SGER:跨膜蛋白的蛋白质组学水平结构生物学
  • 批准号:
    0432322
  • 财政年份:
    2004
  • 资助金额:
    $ 5.8万
  • 项目类别:
    Standard Grant

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