Conference: 2023 Molecular Mechanisms in Evolutions GRC and GRS: Genetic and Phenotypic Evolution at the Organismal, Cellular and Molecular Levels

分子生物学和进化论是地球上生命的两个基本的统一原则。只有通过结合这两个学科的知识，我们才能（i）解开生物体的分子组成如何使它们在过去的环境中生存，（ii）理解当今免疫细胞，癌症组织或微生物种群（包括病原体）中正在进行的进化所带来的挑战，（iii）预测生物体对气候变化和其他人类驱动的当前选择压力的未来反应。2023年戈登进化分子机制会议将聚集分子，医学和进化生物学方面的国际专家，介绍进化变化分子基础的最新发现和不同观点。本次会议将提供一个开放和创造性的讨论，旨在促进参与者之间的合作参与的气氛。简短的演讲和海报将使年轻科学家和他们的想法能够获得受邀演讲者和主席的更有经验的科学家的意见和建议。会议计划将涵盖广泛的主题，包括：蛋白质和RNA的进化，突变和重组率的进化，非遗传变异和遗传，代谢进化，复杂性状的形成。这个GRC的主要目标是鼓励和培养一个研究人员的社区，跨越几个正式的学科，在跨生物尺度的进化变化的分子基础的共同利益。进化科学家包括生态学家、遗传学家、进化、细胞和分子生物学家，以及物理学家和应用数学家。由于学科范围如此广泛，因此为这些不同学科的专家提供一个欣赏进化科学各个领域的重要发现和新技术的机会是很重要的。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

Molecular biology and evolution are the two fundamental unifying principles of life on earth. It is only through the combination of knowledge from these two disciplines that we can (i) unravel how the molecular components of organisms allowed them to survive their past environments, (ii) understand the challenges imposed by present day ongoing evolution occurring in immune cells, cancer tissues or microbial populations, including pathogens, (iii) predict the future responses of organisms to climate changes and other human-driven current selective pressures. The 2023 Gordon Conference on Molecular Mechanisms in Evolution will assemble international experts in molecular, medical, and evolutionary biology to present the latest findings and diverse perspectives on the molecular basis of evolutionary change. This conference will provide an engaging atmosphere for open and creative discussions aimed at stimulating collaboration among the participants. Short talks and posters will provide young scientists and their ideas access to the opinions and suggestions of the more experienced scientists who are invited speakers and chairs. The conference program will cover a wide range of topics including: the evolution of proteins and RNAs, the evolution of mutation and recombination rates, non-genetic variation and inheritance, metabolic evolution, the making of complex traits. The principal goal of this GRC is to encourage and nurture a community of researchers, spanning several formal disciplines, with a shared interest in the molecular basis of evolutionary change across biological scales. Evolutionary scientists include ecologists, geneticists, evolutionary, cellular, and molecular biologists, as well as physicists, and applied mathematicians. With such a wide range of disciplines, it is important to provide an opportunity to experts in these diverse disciplines to appreciate the important discoveries and new technologies from across the breadth of evolutionary science.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.