Conference: Symposium on the Immune System of Bacteria

会议：细菌免疫系统研讨会

• 批准号: 2349218
• 负责人: Philip Kranzusch
• 金额: $ 4.5万
• 依托单位: Dana-Farber Cancer Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-03-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2349218&HistoricalAwards=false
• 关键词: Conference; Symposium; Immune; System; Bacteria

The 2024 Symposium on the Immune System of Bacteria will be the first US meeting to gather the community of scholars working on the myriad of anti-virus immunity systems beyond the best-known CRISPR-Cas systems. There will be a diverse cohort of 19 invited speakers and 15 early-career speakers. Specific initiatives of the meeting include a data presentation and live survey session dedicated to addressing inclusivity in the community, and creation of mentor-mentee pairs to enhance training and accessibility of senior scientists. Bacteria are constantly attacked by viruses (bacteriophages), and have developed molecular systems to protect themselves from virus infection. Some of these systems work by killing the virus, while others kill the bacterium itself before the infection is complete, so that the virus progeny is not formed and the infection is contained. There are more than 100 such systems that are known, the majority of them discovered in the last 5-10 years. One such system, CRISPR-Cas, became widely known because of its biological interest and important biomedical/bioengineering applications. This conference, however, will focus on other, less studied systems. One focus of the conference will be on providing the presentation tribune and mentoring opportunities to the early-career scientists.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

2024年细菌免疫系统研讨会将是美国第一次聚集学者社区的会议，这些学者致力于除最著名的CRISPR-Cas系统之外的无数抗病毒免疫系统。届时将有19位受邀演讲嘉宾和15位创业初期演讲嘉宾。会议的具体倡议包括数据展示和现场调查会议，致力于解决社区的包容性问题，以及创建导师-被指导者对，以加强高级科学家的培训和可及性。细菌不断受到病毒（噬菌体）的攻击，并且已经发展出分子系统来保护自己免受病毒感染。其中一些系统通过杀死病毒起作用，而另一些系统则在感染完全之前杀死细菌本身，这样病毒后代就不会形成，感染也就得到了控制。已知有100多个这样的系统，其中大多数是在过去的5-10年里发现的。其中一个系统，CRISPR-Cas，因其生物学意义和重要的生物医学/生物工程应用而广为人知。然而，这次会议将重点关注其他研究较少的系统。会议的一个重点将是为早期职业科学家提供演讲论坛和指导机会。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。