Composite biomaterials for modulation of dermal fibroblast function

用于调节真皮成纤维细胞功能的复合生物材料

• 批准号: DP0877988
• 负责人: Prof Graeme George
• 金额: $ 27.01万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2012-01-18
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0877988
• 关键词: Composite; biomaterials; modulation; dermal; fibroblast

The successful outcome of this research will revolutionize the way scars are treated for the large number of people who suffer burns and even minor trauma that leads to disfigurement. By using advanced chemical synthesis, biochemical analysis, cell biology and polymer materials science, an intelligent gel sheet will be devised that is able to control the formation of scar tissue and also reduce the effect of existing scars. This will produce improved quality of life for sufferers of severe scarring and have major economic benefits in reduced health costs.

这项研究的成功结果将彻底改变疤痕的治疗方式，因为大量的人遭受烧伤，甚至轻微的创伤，导致毁容。通过使用先进的化学合成，生物化学分析，细胞生物学和高分子材料科学，将设计出一种智能凝胶片，能够控制疤痕组织的形成，并减少现有疤痕的影响。这将提高严重疤痕患者的生活质量，并在降低医疗费用方面具有重大经济效益。