Optimization of Soft-Tissue Balancing for Total-Knee Arthroplasty

本DFG提案的目标是通过计算机模拟支持的体外实验，研究膝关节软组织平衡的各个结构的机制和功能。使用现有文献中的现有数据作为起点，将开发优化的软组织释放系统序列，并定义软组织平衡的客观目标参数。将通过对尸体膝关节标本进行结构化组织切除，然后在机器人辅助试验台上进行刚度研究，对文献中的结果进行补充。此外，收集的数据建立了一个广泛的肌肉骨骼多体模型的膝盖，它可以用来研究软组织平衡的进一步方法的发展基础。该项目是基于模型的患者特定软组织平衡方法模拟的起点，可用于在以下项目中为膝关节TKA创建软组织刨平工具。

The goal of this DFG-Proposal is to investigate the mechanisms and function of individual structures of the knee-joint with regards to soft-tissue balancing by means of in-vitro experiments supported by computer simulations. Using existing currently available data from the literature as a starting point, an optimized systematic sequence of soft-tissue release will be developed, and objective target parameters for soft-tissue balancing defined. The findings from the literature will be complemented by means of structured tissue resections on cadaveric knee specimens followed by stiffness investigations on the robot assisted test rig. Furthermore, the gathered data establisch a basis for the development of a extensive musculoskeletal multi-body model of the knee, which can be used to investigate further approaches for the soft tissue balancing. This project is the starting point for a model based, patient specific, simulation of the soft-tissue-balancing approach, which can be used to create a soft-tissue-planing tool for the knee-TKA in following projects.