Optimization of Soft-Tissue Balancing for Total-Knee Arthroplasty

本dfg提案的目标是通过计算机模拟支持的体外实验，研究膝关节单个结构在软组织平衡方面的机制和功能。以现有文献资料为出发点，制定优化的软组织释放系统序列，确定软组织平衡的目标参数。来自文献的研究结果将通过对尸体膝关节标本进行结构化组织切除的方法进行补充，随后在机器人辅助测试台上进行刚度调查。此外，收集到的数据为建立广泛的膝关节肌肉骨骼多体模型奠定了基础，该模型可用于研究进一步的软组织平衡方法。该项目是基于模型的、患者特异性的软组织平衡方法模拟的起点，可用于在后续项目中为膝关节tka创建软组织规划工具。

The goal of this DFG-Proposal is to investigate the mechanisms and function of individual structures of the knee-joint with regards to soft-tissue balancing by means of in-vitro experiments supported by computer simulations. Using existing currently available data from the literature as a starting point, an optimized systematic sequence of soft-tissue release will be developed, and objective target parameters for soft-tissue balancing defined. The findings from the literature will be complemented by means of structured tissue resections on cadaveric knee specimens followed by stiffness investigations on the robot assisted test rig. Furthermore, the gathered data establisch a basis for the development of a extensive musculoskeletal multi-body model of the knee, which can be used to investigate further approaches for the soft tissue balancing. This project is the starting point for a model based, patient specific, simulation of the soft-tissue-balancing approach, which can be used to create a soft-tissue-planing tool for the knee-TKA in following projects.