Optimization of Soft-Tissue Balancing for Total-Knee Arthroplasty

全膝关节置换术软组织平衡的优化

• 批准号: 271360605
• 负责人: Professor Dr. Christof Hurschler
• 金额: --
• 依托单位: Klinik für Orthopädie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2015
• 资助国家: 德国
• 起止时间: 2014-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/271360605?language=en
• 关键词: Optimization; Soft; Tissue; Balancing; Total

The goal of this DFG-Proposal is to investigate the mechanisms and function of individual structures of the knee-joint with regards to soft-tissue balancing by means of in-vitro experiments supported by computer simulations. Using existing currently available data from the literature as a starting point, an optimized systematic sequence of soft-tissue release will be developed, and objective target parameters for soft-tissue balancing defined. The findings from the literature will be complemented by means of structured tissue resections on cadaveric knee specimens followed by stiffness investigations on the robot assisted test rig. Furthermore, the gathered data establisch a basis for the development of a extensive musculoskeletal multi-body model of the knee, which can be used to investigate further approaches for the soft tissue balancing. This project is the starting point for a model based, patient specific, simulation of the soft-tissue-balancing approach, which can be used to create a soft-tissue-planing tool for the knee-TKA in following projects.

该DFG峰值的目的是通过计算机仿真支持的体外实验来研究膝关节的单个结构的机制和功能。将使用文献中现有的当前可用数据作为起点，将开发出优化的软组织释放的系统序列，并定义了软组织平衡的目标目标参数。文献的发现将通过在尸体膝盖标本上的结构化组织切除量补充，然后对机器人辅助测试钻机进行僵硬研究。此外，收集的数据建立了开发膝盖肌肉骨骼多体多体型模型的基础，该模型可用于研究软组织平衡的进一步方法。该项目是对软组织平衡方法进行基于模型的，特定于患者的模拟的起点，该方法可用于在以下项目中为膝盖-TKA创建软组织平面图。