Optimization of Soft-Tissue Balancing for Total-Knee Arthroplasty

该DFG方案的目的是通过计算机模拟支持的体外实验，研究膝关节各个结构在软组织平衡方面的机制和功能。使用现有的现有文献数据作为起点，将开发软组织释放的优化系统序列，并定义软组织平衡的客观目标参数。通过对身体膝关节标本进行结构性组织切除，然后在机器人辅助试验台上进行僵硬研究，将对文献中的发现进行补充。此外，收集的数据为建立广泛的膝关节肌肉骨骼多体模型奠定了基础，该模型可用于进一步研究软组织平衡的方法。该项目是基于模型的、患者特定的软组织平衡方法的模拟的起点，可用于在以下项目中为膝关节全膝关节置换术创建软组织计划工具。

The goal of this DFG-Proposal is to investigate the mechanisms and function of individual structures of the knee-joint with regards to soft-tissue balancing by means of in-vitro experiments supported by computer simulations. Using existing currently available data from the literature as a starting point, an optimized systematic sequence of soft-tissue release will be developed, and objective target parameters for soft-tissue balancing defined. The findings from the literature will be complemented by means of structured tissue resections on cadaveric knee specimens followed by stiffness investigations on the robot assisted test rig. Furthermore, the gathered data establisch a basis for the development of a extensive musculoskeletal multi-body model of the knee, which can be used to investigate further approaches for the soft tissue balancing. This project is the starting point for a model based, patient specific, simulation of the soft-tissue-balancing approach, which can be used to create a soft-tissue-planing tool for the knee-TKA in following projects.