Advanced micro-architecture and nanotopography for enhanced tissue growth in scaffolds

组织工程支架提供了一种迫切需要的合成生物材料解决方案，以克服来自捐赠者移植的疾病传播。这项工作将结合生物材料化学和设计的表面形貌来触发支架内的骨形成，这是世界上第一次。与国家研究领先者合作，对新支架进行干细胞和动物测试，将提供必要的跨学科方法，为需要骨再生的患者开发新产品。澳大利亚将受益于对医学科学的贡献，开发一种用于快速成型组织工程支架的新设备，保留生物材料研究专业知识，并产生新的生物医学产品。

Tissue engineering scaffolds offer an urgently needed synthetic biomaterials solution to overcome disease transmission from donor transplants. This work will combine biomaterial chemistry and designed surface topography to trigger bone formation within a scaffold for the first time in the world. Collaboration with national research leaders on stem cell and animal testing of the new scaffolds will provide the necessary interdisciplinary approach to generate a new product for patients in need of bone regeneration. Australia will benefit from the contribution to medical science, the development of a new device for rapid prototyping tissue engineering scaffolds, retain biomaterials research expertise, and generate new biomedical products.