Advanced micro-architecture and nanotopography for enhanced tissue growth in scaffolds

先进的微结构和纳米形貌可增强支架中的组织生长

• 批准号: DP0774670
• 负责人: A/Prof Karlis Gross
• 金额: $ 1.25万
• 依托单位: Swinburne University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-03-09
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0774670
• 关键词: Advanced; micro; architecture; nanotopography; enhanced

Tissue engineering scaffolds offer an urgently needed synthetic biomaterials solution to overcome disease transmission from donor transplants. This work will combine biomaterial chemistry and designed surface topography to trigger bone formation within a scaffold for the first time in the world. Collaboration with national research leaders on stem cell and animal testing of the new scaffolds will provide the necessary interdisciplinary approach to generate a new product for patients in need of bone regeneration. Australia will benefit from the contribution to medical science, the development of a new device for rapid prototyping tissue engineering scaffolds, retain biomaterials research expertise, and generate new biomedical products.

组织工程支架提供了一个迫切需要的合成生物材料的解决方案，以克服疾病的传播供体移植。这项工作将结合联合收割机生物材料化学和设计的表面形貌，在世界上第一次在支架内引发骨形成。与国家研究领导人在新支架的干细胞和动物试验方面的合作将提供必要的跨学科方法，为需要骨再生的患者生产新产品。澳大利亚将受益于对医学科学的贡献，开发用于快速成型组织工程支架的新设备，保留生物材料研究专业知识，并产生新的生物医学产品。