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Development of a patient-personalized synapse proteomics technology for advancing precision diagnosis of mental disorders

Development of a patient-personalized synapse proteomics technology for advancing precision diagnosis of mental disorders
开发患者个性化突触蛋白质组学技术以推进精神疾病的精确诊断
批准号:
21K07554
负责人:
TAOUFIQ Zacharie
金额:
$2.5万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2021
资助国家:
日本
项目状态:
已结题
起止时间:
2021-04-01 至 2024-03-31

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中文摘要
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英文摘要
In collaboration with the Budapest Research Center for Natural Sciences, I have received analyzed 3 new iPSC samples coming from Caucasian family having a living schizophrenia individual. The synapse proteomics analysis revealed significant impaired expression of some specific lipid metabolic enzymes compared healthy.I have started a collaboration with RIKEN AIP for building AI/Machine learning tools to interpret and analyze synapse proteomics data from our psychiatric patient cohort.
期刊论文(7)
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科研奖励(0)
会议论文
‘Molecular anatomy of brain synapses from living psychiatric patients’
“活体精神病患者脑突触的分子解剖学”
DOI: --
发表时间: 2022
期刊:
影响因子: --
作者: [西村拡起, 古宮淳一, Zacharie Taoufiq]
通讯作者: Zacharie Taoufiq
Molecular anatomy of brain synapses from living psychiatric patients’
活体精神病患者脑突触的分子解剖学
DOI: --
发表时间: 2021
期刊:
影响因子: --
作者: [Hosoda Yutaka, Ohtani Toshiyuki, Hanazawa Hisashi, Tanaka Mami, Kimura Hiroshi, Ohsako Noriaki, Hashimoto Tasuku, Kobori Osamu, Iyo Masaomi, Nakazato Michiko, Zacharie Taoufiq]
通讯作者: Zacharie Taoufiq
DOI: --
发表时间: 2022
期刊:
影响因子: --
作者: [Noriko Numata, Akiko Nakagawa, Kazuko Yoshioka, Kayoko Isomura, Daisuke Matsuzawa, Rikukage Setsu, Michiko Nakazato & Eiji Shimizu, Zacharie Taoufiq]
通讯作者: Zacharie Taoufiq
Novel peptide drug for treating Alzheimer’s disease.
治疗阿尔茨海默病的新型肽药物。
DOI: --
发表时间: 2022
期刊:
影响因子: --
作者: []
通讯作者:
6
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