Design and synthesis of responsive, elastic, porous single crystalline materials using mechanically interlocked molecules

建立了一条合成具有多个不同官能团的不对称索烃的通用路线。在合成中涉及许多合成挑战。例如，关键中间体的溶解度需要微调，各种保护基团的相容性需要仔细考虑。目前已经可以合成出多种不对称环的索烃，而对于多晶型结构的形成，研究发现索烃配体中的官能团不仅影响晶体的形成，而且影响晶体的形貌。然而，还没有成功地获得足够好以用于进一步表征的晶体。

A general route for the synthesis of asymmetric catenanes with multiple, different functional groups was established. There were many synthetic challenges involved in the synthesis. For example, the solubility of the key intermediates needed to be finely tuned, and the compatibility of various protecting groups required careful consideration. Now a variety of catenanes with asymmetric rings can be readily synthesized.As for the formation of MOF, it was found that the functional groups in catenane ligand affect the formation of the crystal, as well as the morphology of the crystal. However, crystals which are good enough for further characterization have not been successfully obtained.