Study on molecular mechanism of anti-tumor activity by splicing modulation

剪接调节抗肿瘤活性的分子机制研究

• 批准号: 20K15420
• 负责人: Chhipi-Shrestha Jagat
• 金额: $ 2.75万
• 依托单位: Institute of Physical and Chemical Research
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K15420/
• 关键词: spliceostatin A; splicing modulation; proteotoxic stress; aggregation; SSA; cancer; translation; Next gen sequencing; Splicing modulation; Tumor

项目成果

Proteins from translated introns repress global protein synthesis

来自翻译内含子的蛋白质抑制整体蛋白质合成

• 发表时间: 2021
• 作者: Egoshi Syusuke;Dodo Kosuke;Ohgane Kenji;Sodeoka Mikiko;Jagat Krishna Chhipi Shrestha
• 通讯作者: Jagat Krishna Chhipi Shrestha