Analysis of minimal residual disease in ovarian cancer

卵巢癌微小残留病分析

• 批准号: 20K18174
• 负责人: Masuda Kenta
• 金额: $ 2.58万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K18174/
• 关键词: 卵巣癌; 治療抵抗性; 動物モデル; 微小残存病変; マウスモデル; オルガノイド; RNA sequence

项目成果

p53 dysfunction hampers the differentiation and causes the precancerous potency in mouse fallopian tube organoids

p53功能障碍阻碍小鼠输卵管类器官的分化并导致癌前效力

• 发表时间: 2022
• 作者: Shimpei Nagai;Kenta Masuda,Tomohiro Tamura,Tomoko Akahane,Tatsuyuki Chiyoda,Yusuke Kobayashi,Kouji Banno,Mamoru Tanaka,Daisuke Aoki
• 通讯作者: Kenta Masuda,Tomohiro Tamura,Tomoko Akahane,Tatsuyuki Chiyoda,Yusuke Kobayashi,Kouji Banno,Mamoru Tanaka,Daisuke Aoki

Hereditary Ovarian Cancer / Hereditary Breast and Ovarian Cancer:Molecular Mechanism and Clinical Practice

遗传性卵巢癌/遗传性乳腺癌和卵巢癌：分子机制和临床实践

• 发表时间: 2021
• 作者: 澤田祐季;佐藤剛;長屋雅士;吉原紘行;伴野千尋; 松本洋介;松田有希野;吉貝香里;澤田富夫;浮田宗伯;杉浦真弓;Nagai S,Masuda K,Tamura T,Otsuki Y,Suina K,Nobusue H,Akahane T,Chiyoda T,Kobayashi Y,Banno K,Aoki D,Saya H,Nagano O;Masuda K,Artibani M,Nagai S,Kobayashi Y,Banno K,Saya H,Aoki D,Ahmed AA;Tamura T,Masuda K,Nagai S,Otsuki Y,Suina K,Nobusue H,Sampetrean O,Banno K,Aoki D,Saya H,Nagano O;Masuda K,Satake M,Aoki D
• 通讯作者: Masuda K,Satake M,Aoki D

Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor-initiating cells

• DOI: 10.1172/jci.insight.147929
• 发表时间: 2021-06-08
• 期刊: JCI INSIGHT
• 影响因子: 8
• 作者: Artibani, Mara;Masuda, Kenta;Ahmed, Ahmed Ashour
• 通讯作者: Ahmed, Ahmed Ashour

RNA sequencing analysis of ovarian cancer minimal residual disease revealed a metabolic signature that would lead to the development of a new therapeutic strategy

卵巢癌微小残留病的 RNA 测序分析揭示了代谢特征，这将导致新治疗策略的开发

• 发表时间: 2022
• 作者: 澤田祐季;佐藤剛;長屋雅士;齋藤知恵子;吉原紘行;伴野千尋;松本洋介;松田有希野;吉貝香里;澤田富夫;浮田宗伯;杉浦真弓;Kenta Masuda,Ahmed Ashour Ahmed,Tomohiro Tamura,Shimpei Nagai,Yuya Nogami,Kosuke Tsuji,Yusuke Kobayashi,Kouji Banno,Mamoru Tanaka,Daisuke Aoki
• 通讯作者: Kenta Masuda,Ahmed Ashour Ahmed,Tomohiro Tamura,Shimpei Nagai,Yuya Nogami,Kosuke Tsuji,Yusuke Kobayashi,Kouji Banno,Mamoru Tanaka,Daisuke Aoki

Development of a new ovarian cancer mouse model by engineering mouse fallopian tube epithelial organoids

通过改造小鼠输卵管上皮类器官开发新的卵巢癌小鼠模型

• 发表时间: 2022
• 作者: Shimpei Nagai;Kenta Masuda,Tomohiro Tamura,Keiyo Imaeda,Eiji Sugihara,Juntaro Yamasaki,Yuji Otsuki,Hiroyuki Nobusue,Tatsuyuki Chiyoda,Yusuke Kobayashi,Kouji Banno,Daisuke Aoki,Hideyuki Saya,Osamu Nagano
• 通讯作者: Kenta Masuda,Tomohiro Tamura,Keiyo Imaeda,Eiji Sugihara,Juntaro Yamasaki,Yuji Otsuki,Hiroyuki Nobusue,Tatsuyuki Chiyoda,Yusuke Kobayashi,Kouji Banno,Daisuke Aoki,Hideyuki Saya,Osamu Nagano