Establishment of a physiologically-relevant liver model for disease screening

建立用于疾病筛查的生理相关肝脏模型

• 批准号: 20K22491
• 负责人: Danoy Mathieu
• 金额: $ 1.83万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Research Activity Start-up
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-09-11 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K22491/
• 关键词: hiPSCs; HSCs; Liver; Disease; LSECs; Hepatocytes; Inflammation; Immune; Coculture

项目成果

Optimization of In vitro Culture Condition to Maintain Hepatic Stellate Cell in Quiescence

维持肝星细胞静止的体外培养条件优化

• 发表时间: 2021
• 作者: Ya Gong ;Mathieu Danoy ;Taketomo Kido ;Masaki Nishikawa ;Atsushi Miyajima ;Yasuyuki Sakai
• 通讯作者: Yasuyuki Sakai

Influence of CPM-dependent sorting on the multi-omics profile of hepatocyte-like cells matured in microscale biochips

CPM依赖性分选对微型生物芯片中成熟的肝细胞样细胞多组学特征的影响

• DOI: 10.1016/j.bej.2022.108408
• 发表时间: 2022
• 期刊: Biochemical Engineering Journal
• 影响因子: 3.9
• 作者: Mathieu Danoy;Stephane Poulain;Benedikt Scheidecker;Rachid Jellali;Yannick Tauran;Marjorie Leduc;Johanna Bruce;Francoise Gilard;Bertrand Gakiere;Hiroshi Arakawa;Yukio Kato;Soo Hyeon Kim;Taketomo Kido;Atsushi Miyajima;Yasuyuki Sakai;Eric Leclerc
• 通讯作者: Eric Leclerc

Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells

诱导多能干细胞来源的人肝窦内皮样细胞的蛋白质组和代谢组表征

• DOI: 10.1016/j.diff.2021.06.001
• 发表时间: 2021
• 期刊: Differentiation
• 影响因子: 2.9
• 作者: Danoy Mathieu;Jellali Rachid;Tauran Yannick;Bruce Johanna;Leduc Marjorie;Gilard Fran?oise;Gaki?re Bertrand;Scheidecker Benedikt;Kido Taketomo;Miyajima Atsushi;Soncin Fabrice;Sakai Yasuyuki;Leclerc Eric
• 通讯作者: Leclerc Eric