Analysis of the IFN-1 and autophagy mediated pathogenesis in inflammatory bowel disease

IFN-1和自噬介导的炎症性肠病发病机制分析

• 批准号: 20K22895
• 负责人: Ito Go
• 金额: $ 1.83万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Research Activity Start-up
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-09-11 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K22895/
• 关键词: IFN-1; Atg16L1; アポトーシス; ネクロプトーシス; RIP1キナーゼ; RIP1; autophagy; apoptosis; necroptosis; IBD

项目成果

Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.

• DOI: 10.1136/gutjnl-2020-323868
• 发表时间: 2021-04-22
• 期刊: Gut
• 影响因子: 24.5
• 作者: Zheng T;Ellinghaus D;Juzenas S;Cossais F;Burmeister G;Mayr G;Jørgensen IF;Teder-Laving M;Skogholt AH;Chen S;Strege PR;Ito G;Banasik K;Becker T;Bokelmann F;Brunak S;Buch S;Clausnitzer H;Datz C;DBDS Consortium;Degenhardt F;Doniec M;Erikstrup C;Esko T;Forster M;Frey N;Fritsche LG;Gabrielsen ME;Gräßle T;Gsur A;Gross J;Hampe J;Hendricks A;Hinz S;Hveem K;Jongen J;Junker R;Karlsen TH;Hemmrich-Stanisak G;Kruis W;Kupcinskas J;Laubert T;Rosenstiel PC;Röcken C;Laudes M;Leendertz FH;Lieb W;Limperger V;Margetis N;Mätz-Rensing K;Németh CG;Ness-Jensen E;Nowak-Göttl U;Pandit A;Pedersen OB;Peleikis HG;Peuker K;Rodriguez CL;Rühlemann MC;Schniewind B;Schulzky M;Skieceviciene J;Tepel J;Thomas L;Uellendahl-Werth F;Ullum H;Vogel I;Volzke H;von Fersen L;von Schönfels W;Vanderwerff B;Wilking J;Wittig M;Zeissig S;Zobel M;Zawistowski M;Vacic V;Sazonova O;Noblin ES;23andMe Research Team;Farrugia G;Beyder A;Wedel T;Kahlke V;Schafmayer C;D'Amato M;Franke A
• 通讯作者: Franke A