The role of OEP16 and OEP40 in cold acclimation (B05)

OEP16和OEP40在冷驯化中的作用（B05）

• 批准号: 317552149
• 金额: --
• 依托单位: Lehrstuhl für Biochemie und Physiologie der Pflanzen
• 依托单位国家: 德国
• 项目类别: CRC/Transregios
• 财政年份: 2016
• 资助国家: 德国
• 起止时间: 2015-12-31 至 2019-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/317552149?language=en
• 关键词: role; OEP16; OEP40; cold; acclimation

We have recently identified two chloroplast outer envelope localized solute channels, namely OEP16.1 and OEP40, which are also involved in cold acclimation in Arabidopsis. Our goal is to understand how OEP16.1 and OEP40 contribute to metabolic networking and signalling during cold acclimation. This will be achieved 1. by obtaining a detailed understanding of their biochemical properties, e.g. substrate specificity, regulation of gating and protein structure, and 2. by analysing the transcriptional, post-translational and metabolic changes, which depend on OEP16.1 and OEP40 in vivo in an organelle and tissue-specific quantitative manner during the acclimation process.

我们最近发现了两个叶绿体外被膜定位的溶质通道，即OEP 16.1和OEP 40，这也参与了拟南芥的冷驯化。我们的目标是了解OEP 16.1和OEP 40如何在冷适应期间促进代谢网络和信号传导。这将实现1。通过获得其生化特性的详细了解，例如底物特异性，门控和蛋白质结构的调节，和2.通过分析转录，翻译后和代谢的变化，这取决于OEP 16.1和OEP 40在体内的细胞器和组织特异性定量方式在驯化过程中。