Mechanisms and components of GUN1/GLK signalling and its relevance for acclimation (C05)

GUN1/GLK 信号传导的机制和成分及其与适应的相关性 (C05)

• 批准号: 317556510
• 金额: --
• 依托单位: Lehrstuhl für Molekularbiologie der Pflanzen
• 依托单位国家: 德国
• 项目类别: CRC/Transregios
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/317556510?language=en
• 关键词: Mechanisms; components; GUN1; GLK; signalling

The plastid protein GENOMES UNCOUPLED 1 (GUN1) and the nuclear transcription factors GOLDEN-LIKE1 and 2 (GLK1 and 2) operate in the same retrograde signalling pathway defined by de-repressed LHCB1 marker gene expression during treatment with norflurazon or lincomycin. We found in preceding work that GUN1 and GLK play a role in acclimation to cold. Our project includes: (i) Physiological characterisation of GUN1-GLK functions in the cold, (ii) Identification of novel of GUN1-GLK signalling components by genetic screens, (iii) Dissection of cis-regulatory elements of GUN1-mediated GLK transcriptional regulation, and (iv) Characterization of GLK targets.

质体蛋白基因组不偶联1（GUN 1）和核转录因子GOLDEN-LIKE 1和2（GLK 1和2）在相同的逆行信号通路中发挥作用，该通路由去阻遏的LHCB 1标记基因表达在氟草松或林可霉素治疗期间定义。我们在前期工作中发现GUN 1和GLK在冷适应中起作用。我们的项目包括：（i）寒冷中GUN 1-GLK功能的生理学表征，（ii）通过遗传筛选鉴定新的GUN 1-GLK信号传导组分，（iii）剖析GUN 1介导的GLK转录调节的顺式调节元件，和（iv）GLK靶标的表征。