Elucidation of the molecular mechanism of cancer-related fibroblast induction and regulation of the tumor microenvironment based on its inhibition
Elucidation of the molecular mechanism of cancer-related fibroblast induction and regulation of the tumor microenvironment based on its inhibition
批准号:
20H00518
负责人:
Saya Hideyuki
金额:
$29.2万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2020
资助国家:
日本
项目状态:
已结题
起止时间:
2020-04-01 至 2023-03-31
中文摘要
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英文摘要
期刊论文(21)
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Therapeutic strategies based on actin cytoskeleton dynamics for targeting chemoresistant osteosarcoma stem cells
基于肌动蛋白细胞骨架动力学的靶向化疗耐药骨肉瘤干细胞的治疗策略
DOI:
--
发表时间:
2022
期刊:
影响因子:
--
作者:
[信末博行, 清水孝恒, 高橋信博, 山口さやか, 杉原英志, 大西伸幸, 佐谷秀行]
通讯作者:
佐谷秀行
DOI:
10.1172/jci153626
发表时间:
2022-03-15
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
[Ando T, Tai-Nagara I, Sugiura Y, Kusumoto D, Okabayashi K, Kido Y, Sato K, Saya H, Navankasattusas S, Li DY, Suematsu M, Kitagawa Y, Seiradake E, Yamagishi S, Kubota Y]
通讯作者:
Kubota Y
Inhibition of MKL1 enhances the effects of anticancer drugs in chemoresistant osteosarcoma cells
抑制 MKL1 可增强抗癌药物对化疗耐药骨肉瘤细胞的作用
DOI:
--
发表时间:
2022
期刊:
影响因子:
--
作者:
[信末博行, 清水孝恒, 高橋信博, 山口さやか, 杉原英志, 大西伸幸, 佐谷秀行]
通讯作者:
佐谷秀行
DOI:
10.1111/cas.14504
发表时间:
2020-06-22
期刊:
CANCER SCIENCE
影响因子:
5.7
作者:
[Arima, Yoshimi, Nobusue, Hiroyuki, Saya, Hideyuki]
通讯作者:
Saya, Hideyuki
DOI:
10.1158/0008-5472.can-19-3993
发表时间:
2020-10-15
期刊:
CANCER RESEARCH
影响因子:
11.2
作者:
[Sugihara, Eiji, Hashimoto, Norisato, Saya, Hideyuki]
通讯作者:
Saya, Hideyuki
共 6 条
Elucidation of cancer treatment resistance mechanism based on methionine metabolism and identification of novel therapeutic targets
-
批准号:21K19416
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.16万
-
财政年份:2021
-
负责人:Saya Hideyuki
-
依托单位:
Development of new therapeutic agents for pancreatic cancer targeting 14-3-3dzeta
-
批准号:19K22568
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.08万
-
财政年份:2019
-
负责人:Saya Hideyuki
-
依托单位:
Elucidation of underlyingmechanism of MKL1-mediated induction of cancer associated fibroblasts and its clinical applications
-
批准号:17H01401
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$27.29万
-
财政年份:2017
-
负责人:Saya Hideyuki
-
依托单位:
Analysis of escaping mechanism from immune system by microenvironment of cancer stem cells
-
批准号:15K14384
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2015
-
负责人:Saya Hideyuki
-
依托单位:
Development of a novel anti-invasion therapy targeting the glioma stem cell/endothelial cell invasion complex
-
批准号:25253085
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$28.87万
-
财政年份:2013
-
负责人:Saya Hideyuki
-
依托单位:
海外基金