ショットガンメタゲノミクスによるシロアリ腸内微生物群集の進化動態の解明

2022年3月，我成功地为自己的博士论文辩护。论文第一章或第一个目标已被《微生物组》杂志接受(影响因子14.65)。我考察了白蚁肠道微生物功能在1.5亿年进化过程中的演变，并完成了项目第二个目标的分析、数字和稿件撰写，在该项目中，我分析了白蚁进化历史上202个白蚁样本的肠道微生物组成。该项目的稿件已基本准备好提交给一家高影响力的期刊。最后，作为论文第三章的一部分，分析了项目的最后一个目标。本章涉及使用系统发生学方法研究微生物基因家族的进化，以调查水平基因转移和从环境中多次获取对代谢基因的作用。论文第一章对十大微生物基因家族进行了研究，目前已扩展到剩下的一百个基因家族。剧本已经标准化，手稿将在接下来的几个月内准备好。

I successfully defended my PhD thesis in March, 2022. The thesis chapter one orthe first AIM has been accepted in the Microbiome journal (impact factor 14.65). I examined the evolution of termite gut microbial functions across 150 million years of evolution.I also finished the analysis, figures, and manuscript writing for the second AIM of the project, in which I analyzed the gut microbial composition in 202 termite samples across termite evolutionary history. The manuscript for this project is almost ready for submission to a high-impact factor journal.Finally, the last AIM of the project was analyzed as part of the third chapter of the thesis. This chapter involved examining microbial gene family evolution using phylogenetic methods to investigate the role of Horizonal Gene Transfer and multiple acquisitions from the environment on metabolic genes. The top ten microbial gene families were examined in the thesis chapter, which is now being scaled up to the remaining hundred gene families. The scripts have been standardized, and the manuscript will be ready in the next few months.