Role of NKG2D immunity in myelodysplastice syndrome

NKG2D 免疫在骨髓增生异常综合征中的作用

• 批准号: 19K08821
• 负责人: Sonoki Takashi
• 金额: $ 2.16万
• 依托单位: Wakayama Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2019
• 资助国家: 日本
• 起止时间: 2019-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19K08821/
• 关键词: 骨髄異形成症候群; NKG2D免疫; 自己炎症性腸疾患; NKG2D介在免疫; 骨髄不全症候群; LIG4変異; LIG4遺伝子変異

项目成果

Soluble NKG2D Ligands Are Potential Biomarkers and Sentinels of Immune-Mediated Bone Marrow Injury in Bone Marrow Failure Syndromes.

可溶性 NKG2D 配体是骨髓衰竭综合征中免疫介导的骨髓损伤的潜在生物标志物和哨兵。

• DOI: 10.1159/000500657
• 发表时间: 2020
• 期刊: Acta Haematol.
• 作者: Murata S;Mushino T;Hosoi H;Kuriyama K;Nishikawa A;Nagakura S;Horikawa K;Yonemura Y;Nakakuma H;Sonoki T;Hanaoka N.
• 通讯作者: Hanaoka N.

Identification of a novel CCDC22 mutation in a patient with severe Epstein?Barr virus-associated hemophagocytic lymphohistiocytosis and aggressive natural killer cell leukemia

重度 Epstein?Barr 病毒相关噬血细胞性淋巴组织细胞增多症和侵袭性自然杀伤细胞白血病患者中新型 CCDC22 突变的鉴定

• DOI: 10.1007/s12185-019-02595-0
• 发表时间: 2019
• 期刊: International Journal of Hematology
• 影响因子: 2.1
• 作者: Yamashita Y;Nishikawa A;Iwahashi Y;Fujimoto M;Sasaki I;Mishima H;Kinoshita A;Hemmi H;Kanazawa N;Ohshima K;Imadome KI;Murata SI、Yoshiura KI;Kaisho T;Sonoki T;Tamura S
• 通讯作者: Tamura S

Role of BM aspiration clots: comparison of clots, biopsies, and smears for evaluating BM cellularity

骨髓抽吸凝块的作用：比较凝块、活检和涂片以评估骨髓细胞结构

• 发表时间: 2021
• 作者: Ken Tanaka;Hiroki Hosoi;Rieko Kodama;Shotaro Tabata;Takayuki Hiroi;Yohei Kida;Toshiki Mushino;Shogo Murata;Shinobu Tamura;Takeshi Ikeda;Takashi Sonoki
• 通讯作者: Takashi Sonoki

Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib.

• DOI: 10.3390/ijms21176314
• 发表时间: 2020-08-31
• 期刊: International journal of molecular sciences
• 影响因子: 5.6
• 作者: Yamashita Y;Morita S;Hosoi H;Kobata H;Kishimoto S;Ishibashi T;Mishima H;Kinoshita A;Backes BJ;Yoshiura KI;Papa FR;Sonoki T;Tamura S
• 通讯作者: Tamura S

Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell lines.

• DOI: 10.1016/j.gene.2021.145421
• 发表时间: 2021-03-30
• 期刊: Gene
• 影响因子: 3.5
• 作者: Hosoi H;Niibori-Nambu A;Nah GSS;Bahirvani AG;Mok MMH;Sanda T;Kumar AP;Tenen DG;Ito Y;Sonoki T;Osato M
• 通讯作者: Osato M