B7H3 as a promising therapeutic target for endometrial cancer

B7H3 作为子宫内膜癌有前景的治疗靶点

• 批准号: 19K09769
• 负责人: Ihira Kei
• 金额: $ 2.75万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2019
• 资助国家: 日本
• 起止时间: 2019-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19K09769/
• 关键词: B7H3; 子宮体癌; Ｂ７Ｈ３; 体癌; Endometrial cancer

项目成果

EIF5A2 controls ovarian tumor growth and metastasis by promoting epithelial to mesenchymal transition via the TGFβ pathway.

• DOI: 10.1186/s13578-021-00578-5
• 发表时间: 2021-04-07
• 期刊: Cell & bioscience
• 影响因子: 7.5
• 作者: Zhao G;Zhang W;Dong P;Watari H;Guo Y;Pfeffer LM;Tigyi G;Yue J
• 通讯作者: Yue J

Long non-coding RNA NEAT1 drives aggressive endometrial cancer progression via sponging microRNA-361

长非编码 RNA NEAT1 通过海绵 microRNA-361 驱动侵袭性子宫内膜癌进展

• 发表时间: 2020
• 作者: Peixin Dong;Daozhi Xu;Kei Ihira;Yosuke Konno and Hidemichi Watari
• 通讯作者: Yosuke Konno and Hidemichi Watari

PD-L1 is a tumor suppressor in aggressive endometrial cancer cells and its expression is regulated by miR-216a

PD-L1 是侵袭性子宫内膜癌细胞中的肿瘤抑制因子，其表达受 miR-216a 调节

• 发表时间: 2021
• 作者: Daozhi Xu;Peixin Dong;Kei Ihira;Yosuke Konno and Hidemichi Watari
• 通讯作者: Yosuke Konno and Hidemichi Watari

LncRNA NEAT1-mediated miR-361 downregulation contributes to EMT and sphere formation of cervical cancer cells via increasing HSP90 expression

LncRNA NEAT1介导的miR-361下调通过增加HSP90表达促进宫颈癌细胞的EMT和球形形成

• 发表时间: 2020
• 作者: Peixin Dong;Daozhi Xu;Kei Ihira;Yosuke Konno and Hidemichi Watari
• 通讯作者: Yosuke Konno and Hidemichi Watari

Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes

• DOI: 10.1186/s13046-019-1306-9
• 发表时间: 2019-07-08
• 期刊: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
• 影响因子: 11.3
• 作者: Dong, Peixin;Xiong, Ying;Watari, Hidemichi
• 通讯作者: Watari, Hidemichi