Study to develop therapeutic strategy of neurodegenerative disorders by targeting on CRMP
Study to develop therapeutic strategy of neurodegenerative disorders by targeting on CRMP
批准号:
18K06511
负责人:
Ohshima Toshio
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2018
资助国家:
日本
项目状态:
已结题
起止时间:
2018-04-01 至 2021-03-31
中文摘要
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英文摘要
期刊论文(5)
专著(0)
科研奖励(0)
会议论文
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Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson's disease via suppressions of CRMP2 phosphorylation and microglial activation
羊毛硫氨酸酮亚胺酯通过抑制 CRMP2 磷酸化和小胶质细胞激活改善 MPTP 诱导的帕金森病小鼠模型的结果
DOI:
10.1016/j.jns.2020.116802
发表时间:
2020
期刊:
Journal of the Neurological Sciences
影响因子:
4.4
作者:
[Togashi Kentaro, Hasegawa Masaya, Nagai Jun, Kotaka Ken, Yazawa Arina, Takahashi Miyuki, Masukawa Daiki, Goshima Yoshio, Hensley Kenneth, Ohshima Toshio]
通讯作者:
Ohshima Toshio
Loss of Collapsin Response Mediator Protein 4 Attenuates 6-Hydroxydopamine-Induced Impairments in a Mouse Model of Parkinson’s Disease
帕金森病小鼠模型中崩溃蛋白反应介导蛋白 4 的缺失可减轻 6-羟基多巴胺诱导的损伤
DOI:
10.1007/s11064-020-03086-z
发表时间:
2020
期刊:
Neurochemical Research
影响因子:
4.4
作者:
[Li Wenting, Goshima Yoshio, Ohshima Toshio]
通讯作者:
Ohshima Toshio
Genetic inhibition of CRMP2 phosphorylation delays Wallerian degeneration after optic nerve injury
CRMP2磷酸化的基因抑制可延缓视神经损伤后的沃勒变性
DOI:
10.1016/j.bbrc.2019.05.060
发表时间:
2019
期刊:
BBRC
影响因子:
--
作者:
[Kinoshita Y, Kondo S, Takahashi K, Nagai J, Wakatsuki S, Araki T, Goshima Y, Ohshima T]
通讯作者:
Ohshima T
DOI:
10.1038/s41598-019-43658-w
发表时间:
2019-05-10
期刊:
SCIENTIFIC REPORTS
影响因子:
4.6
作者:
[Kondo, Shunsuke, Takahashi, Kazuya, Ohshima, Toshio]
通讯作者:
Ohshima, Toshio
Elucidation of roles of CRMP in neural circuit formation and regeneration and application for the treatment of spinal cord injury
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批准号:26430043
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2014
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负责人:Ohshima Toshio
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依托单位:
海外基金