Protective effect of early administration of caffeine in newborn animal models of ventilator induced lung injury and chronic lung disease.

早期给予咖啡因对呼吸机引起的肺损伤和慢性肺病新生动物模型的保护作用。

• 批准号: 18K07854
• 负责人: HUSSEIN MOHAMED
• 金额: $ 2.83万
• 依托单位: Saitama Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2018
• 资助国家: 日本
• 起止时间: 2018-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-18K07854/
• 关键词: 新生児; 早産; 肺損傷; 機械式人工呼吸器; 肺の病理学; 肺の超音波検査; newborn; chronic lung disease; animal model; oxygen need; lung ultrasound score; cytokines; Preterm infant; Caffeine; Ventilatory lung injury; respiratory distress; Chronic Lung Disease; Respiratory

项目成果

Caffeine attenuated needs for high supplementary oxygen and reduced respiratory distress lung ultrasound scores in a neonatal model of respiratory distress with ventilatory induced lung injury.

在呼吸窘迫伴通气性肺损伤的新生儿模型中，咖啡因减弱了对高补充氧气的需求，并降低了呼吸窘迫肺部超声评分。

• 发表时间: 2021
• 作者: Kagitani-Shimono K;Hayashi R;Iwatani Y;Tominaga K;Nabatame S;Oshino S; Kato H;Kishima H;Hatazawa J;Taniike M.;下野九理子;下野九理子;下野九理子;岩谷 祥子,下野 九理子;下野九理子;[下野九理子];MOHAMED HAMED HUSSEIN SALEH
• 通讯作者: MOHAMED HAMED HUSSEIN SALEH