Development of a novel technique for the trans-synaptic gene manipulation
Development of a novel technique for the trans-synaptic gene manipulation
批准号:
24650175
负责人:
FUJIMOTO Satoshi
金额:
$2.5万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
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英文摘要
Neural circuits are established by specific neuronal connections via synapses. Therefore, gene manipulation system in a circuit level could be a powerful tool to understand the structural basis of neural computation. In this study, we attempted to make a novel genetically-encoded protein that enables us to trans-synaptically visualize and manipulate a specific neural circuit.
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SeeDB: an aqueous optical clearing agent for imaging intact fluorescence and morphology in the mouse brain.
SeeDB:一种水性光学透明剂,用于对小鼠大脑中完整的荧光和形态进行成像。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Meng-tsen Ke, Satoshi Fujimoto, Takeshi Imai]
通讯作者:
Takeshi Imai
簡便で生体試料にやさしい組織透明化試薬「SeeDB」を開発 プレスリリース
开发“SeeDB”,一种简单且适用于生物样品的组织透明化试剂 新闻稿
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
SeeDB : an aqueous optical clearing agent for imaging intact fluorescence and morphology in the mouse brain
SeeDB:一种水性光学透明剂,用于对小鼠大脑中完整的荧光和形态进行成像
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Meng-tsen Ke, Satoshi Fujimoto, Takeshi Imai]
通讯作者:
Takeshi Imai
Optical Clearing Using SeeDB
使用 SeeDB 进行光学清算
DOI:
--
发表时间:
2014
期刊:
Bio-protocol
影响因子:
0.8
作者:
[Meng-Tsen Ke, Satoshi Fujimoto, Takeshi Imai]
通讯作者:
Takeshi Imai
SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction
DOI:
10.1038/nn.3447
发表时间:
2013-08-01
期刊:
NATURE NEUROSCIENCE
影响因子:
25
作者:
[Ke, Meng-Tsen, Fujimoto, Satoshi, Imai, Takeshi]
通讯作者:
Imai, Takeshi
Novel phenomena and strong correlation effects in noncentrosymmetric superconductors
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批准号:18540347
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.45万
-
财政年份:2006
-
负责人:FUJIMOTO Satoshi
-
依托单位:
Geometrical Frustration in Strongly Correlated Electron Systems
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批准号:14540356
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2002
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负责人:FUJIMOTO Satoshi
-
依托单位:
海外基金