Fabrication of function-switchable surfaces in metallic biomaterials

金属生物材料中功能可切换表面的制造

• 批准号: 24656420
• 负责人: UEDA Masato
• 金额: $ 2.66万
• 依托单位: Kansai University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-24656420/
• 关键词: 生体材料; 機能切換え; 光照射; 機能切り替え

Hydroxyapatite (HAp) is known to precipitate on bioactive materials by soaking in simulated body fluid (SBF). The formation of HAp on TiO2 and ZrO2 surfaces under ultraviolet (UV) irradiation was investigated. HAp formation on ZrO2 surface was not sensitive to heat treatment and UV irradiation. In contrast, the HAp formation on the TiO2 in SBF was strongly influenced by heat treatments and UV irradiation. Hydroxyl group density on TiO2 surface could be decreased by the heat treatment. Then the density could be recovered by previous UV irradiation, it led to promotion of HAp formation. This means recovery of bioactivity on the TiO2 surface. The UV light produced electron-hole pairs in the TiO2, and the photogenerated holes that migrated to the surface repelled the positively charged ions in the solution. As a consequence, the continuous UV irradiation suppressed the formation of HAp. These results suggest that several functions in TiO2 might be switched by light irradiation.

羟基磷灰石（HAp）在模拟体液（SBF）中会在生物活性材料上沉淀。研究了紫外光照射下羟基磷灰石（HAp）在TiO 2和ZrO 2表面的形成。HAp在ZrO 2表面上的形成对热处理和UV照射不敏感。与此相反，HAp的形成上的TiO 2在SBF的强烈影响热处理和紫外线照射。热处理可以降低TiO 2表面的羟基密度。然后通过先前的UV照射可以恢复密度，这导致促进HAp的形成。这意味着TiO 2表面上的生物活性恢复。紫外光在TiO 2中产生电子-空穴对，迁移到表面的光生空穴排斥溶液中的带正电荷的离子。因此，连续的UV照射抑制了HAp的形成。这些结果表明，在TiO 2的几个功能可能会被光照射切换。

项目成果

Photo-Induced Formation of Hydroxyapatite on TiO2 and ZrO2 in SBF

SBF 中 TiO2 和 ZrO2 上光诱导形成羟基磷灰石

• 作者: M. Kato;T. Kinoshita;M. Ueda;M. Ikeda
• 通讯作者: M. Ikeda

Chemical-Hydrothermal Synthesis of Bioactive/Bioinert Oxide Films on CP Ti

CP Ti 上生物活性/生物惰性氧化膜的化学水热合成

• 作者: M. Ueda;M. Ikeda;K. Kuroda;R. Langford;J. Skepper;R.E. Cameron;S.M. Best
• 通讯作者: S.M. Best

Formation of Hydroxyapatite on TiO_2 and ZrO_2 in Simulated Body Fluid under UV Irradiation

紫外照射下模拟体液中TiO_2和ZrO_2上羟基磷灰石的形成

• 发表时间: 2014
• 作者: M. Ueda;M. Kato;M. Ikeda
• 通讯作者: M. Ikeda

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