Formulation of Liquid-Liquid-Liquid Reaction System in Microreactor

微反应器中液-液-液反应体系的制定

• 批准号: 24656483
• 负责人: KUSAKABE Katsuki
• 金额: $ 2.5万
• 依托单位: Sojo University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-24656483/
• 关键词: マイクロリアクター; 相関移動; 有機合成; 液滴; 相間移動

When potassium hydroxide solution, benzene and dichloromethane including equimolar mixture of benzyltriphenylphosphonium bromide and p-methoxybenzaldehyde was fed through a cross joint into a microreactor, segmented flow consisting water droplet and oil droplets was formed and the Wittig reaction proceeded in the tube. The reaction yield in liquid-liquid-liquid reaction system was higher than that in liquid-liquid one due to the contribution of mass transfer effect.

当氢氧化钾溶液、苯和二氯甲烷（包括苄基三苯基溴化鏻和对甲氧基苯甲醛的等摩尔混合物）通过十字接头进料到微反应器中时，形成由水滴和油滴组成的分段流，Wittig反应在管中进行。液-液-液反应体系的反应产率高于液-液反应体系，这是由于传质效应的贡献。