Comprehensive analysis of alternative splicing variants identified from tonotopical differences in the mouse cochlea

从小鼠耳蜗的音调差异中鉴定出的选择性剪接变异体的综合分析

• 批准号: 25670715
• 负责人: YOSHIMURA Hidekane
• 金额: $ 2.33万
• 依托单位: Shinshu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2013
• 资助国家: 日本
• 起止时间: 2013-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-25670715/
• 关键词: 内耳; 遺伝子発現; 難聴; 耳科学; 聴覚; 遺伝子; マイクロアレイ

项目成果

Deafness gene expression patterns in the mouse cochlea found by microarray analysis.

• DOI: 10.1371/journal.pone.0092547
• 发表时间: 2014
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Yoshimura H;Takumi Y;Nishio SY;Suzuki N;Iwasa Y;Usami S
• 通讯作者: Usami S

USH2 caused by GPR98 mutation diagnosed by massively parallel sequencing in advance of the occurrence of visual symptoms.

在视觉症状出现之前通过大规模并行测序诊断出GPR98突变引起的USH2。

• DOI: 10.1177/0003489415574070
• 发表时间: 2015
• 期刊: The Annals of otology, rhinology, and laryngology
• 作者: Moteki,Hideaki;Yoshimura,Hidekane;Azaiez,Hela;Booth,KevinT;Shearer,AEliot;Sloan,ChristinaM;Kolbe,DianaL;Murata,Toshinori;Smith,RichardJH;Usami,Shin-Ichi
• 通讯作者: Usami,Shin-Ichi

Identification of a Novel CLRN1 Gene Mutation in Usher Syndrome Type 3: Two Case Reports.

3 型亚瑟综合症中新型 CLRN1 基因突变的鉴定：两个病例报告。

• 发表时间: 2015
• 期刊: Ann Otol Rhinol Laryngol
• 作者: Yoshimura H;Oshikawa C;Nakayama J;Moteki H;Usami SI.
• 通讯作者: Usami SI.

Laser-capture micro dissection combined with next-generation sequencing analysis of cell type-specific deafness gene expression in the mouse cochlea

• DOI: 10.1016/j.heares.2017.02.017
• 发表时间: 2017-05-01
• 期刊: HEARING RESEARCH
• 影响因子: 2.8
• 作者: Nishio, Shin-ya;Takumi, Yutaka;Usami, Shin-ichi
• 通讯作者: Usami, Shin-ichi