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Explicit representation of holistic antibody repertoire by exhaustive RNA sequencing and the antibody expression by reverse genetics.

Explicit representation of holistic antibody repertoire by exhaustive RNA sequencing and the antibody expression by reverse genetics.
通过详尽的 RNA 测序明确表示整体抗体库,并通过反向遗传学表达抗体。
批准号:
15K15159
负责人:
OHNISHI Kazuo
金额:
$2.41万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2018-03-31

项目摘要

项目成果

OHNISHI Kazuo的其他基金

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期刊论文(12)
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科研奖励(0)
会议论文
Distorted antibody repertoire developed in the absence of pre-B cell receptor formation
在没有前 B 细胞受体形成的情况下开发出扭曲的抗体库
DOI: 10.1016/j.bbrc.2017.11.171
发表时间: 2018
期刊: Biochem. Biophys. Res. Commun.
影响因子: --
作者: [Lin Sun, Naoko Kono, Takeyuki Shimizu, Hiroyuki Toh, Hanbing Xue, Osamu Numata, Manabu Ato, Shigeyuki Itamura, Kazuo Ohnishi]
通讯作者: Kazuo Ohnishi
Search for a "Universal-IgL" that is able to associate with wide range of IgH species and the optimization of NGS-predicted antibody synthesis
寻找能够与多种 IgH 物种相关的“通用 IgL”以及 NGS 预测抗体合成的优化
DOI: --
发表时间: 2015
期刊:
影响因子: --
作者: [SUN Lin, KONO Naoko, SHIMIZU Takeyuki, OHNISHI Kazuo]
通讯作者: OHNISHI Kazuo
Deep Sequence Landscape of Antibody Repertoire and its Antigen Responding Dynamics of Individual Mice Analyzed by Next Generation Sequencer (NGS)
通过下一代测序仪 (NGS) 分析抗体库的深层序列景观及其个体小鼠的抗原反应动态
DOI: --
发表时间: 2015
期刊:
影响因子: --
作者: [KONO Naoko, XUE Hanbing, SUN Lin, SHIMIZU Takeyuki, OHNISHI Kazuo]
通讯作者: OHNISHI Kazuo
Examination of “Universal Light Chain” models that can be paired with a wide spectrum of immunoglobulin heavy chains maintaining their antigen-binding specificities
检查“通用轻链”模型,该模型可以与广泛的免疫球蛋白重链配对,保持其抗原结合特异性
DOI: --
发表时间: 2017
期刊:
影响因子: --
作者: [薛漢兵, 孫琳, 大西和夫]
通讯作者: 大西和夫
10
    Studies on the freme-work of mucosal immunity by the functional analysis of novel cadherin family molecule
    • 批准号:
      14570290
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.5万
    • 财政年份:
      2002
    • 负责人:
      OHNISHI Kazuo
    • 依托单位: