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Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus

Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus
人诱导多能干细胞来源的肝细胞系作为宿主与乙型肝炎病毒相互作用的新模型
批准号:
15K15285
负责人:
Asahina Yasuhiro
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2017-03-31

项目摘要

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期刊论文(38)
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会议论文
Expression of IFN lambda 4 in liver is closely associated with non-response to antiviral therapy through the regulation of basal expression of ISGs in chronic hepatitis C patients but not in hepatitis B.
肝脏中 IFN lambda 4 的表达通过调节慢性丙型肝炎患者 ISG 的基础表达与抗病毒治疗无反应密切相关,但在乙型肝炎中则不然。
DOI: --
发表时间: 2015
期刊:
影响因子: --
作者: [Murakawa M, Asahina Y, Kawai-Kitahata F, Nagata H, Kaneko S, Nitta S, Watanabe T, Itsui Y, Nakagawa M, Kakinuma S, Iijima S, Tanaka Y, Watanabe M, Tanaka Y]
通讯作者: Tanaka Y
DOI: 10.1038/srep34652
发表时间: 2016-10-05
期刊: Scientific reports
影响因子: 4.6
作者: [Nitta S, Asahina Y, Matsuda M, Yamada N, Sugiyama R, Masaki T, Suzuki R, Kato N, Watanabe M, Wakita T, Kato T]
通讯作者: Kato T
DOI: 10.1371/journal.pone.0165339
发表时间: 2016
期刊: PloS one
影响因子: 3.7
作者: [Itakura J, Kurosaki M, Hasebe C, Osaki Y, Joko K, Yagisawa H, Sakita S, Okushin H, Satou T, Hisai H, Abe T, Tsuji K, Tamada T, Kobashi H, Mitsuda A, Ide Y, Ogawa C, Tsuruta S, Takaguchi K, Murakawa M, Asahina Y, Enomoto N, Izumi N]
通讯作者: Izumi N
Human induce pluripotent stem cell-dereived hepatic progenitor-like cells and hepatocyte-like cells as a model for interaction between hepatitis B virus and host cells.
人类诱导多能干细胞来源的肝祖细胞样细胞和肝细胞样细胞作为乙型肝炎病毒与宿主细胞之间相互作用的模型。
DOI: --
发表时间: 2015
期刊:
影响因子: --
作者: [Kaneko S, Kakinuma S, Asahina Y, Kamiya A, Nitta S, Tsunoda T, Miyosi M, Nagata H, Goto F, Otani S, Murakawa M, Kawai-Kitahata F, Itsui Y, Nakagawa M, Azuma S, Watanabe M]
通讯作者: Watanabe M
23
    Analyses of genomic alteration and mechanisms responsible for hepatocarcinogenesis using deep sequencing and human iPS cells
    • 批准号:
      19H03635
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.15万
    • 财政年份:
      2019
    • 负责人:
      Asahina Yasuhiro
    • 依托单位:
    Development of human iPS cell-derived model for hepatocarcinogenesis
    • 批准号:
      17K19647
    • 项目类别:
      Grant-in-Aid for Challenging Research (Exploratory)
    • 资助金额:
      $4.16万
    • 财政年份:
      2017
    • 负责人:
      Asahina Yasuhiro
    • 依托单位:
    Comprehensive analyses of gene mutational profile and viral integration in hepatocellular carcinoma and development of novel human iPS cells-derived disease model
    • 批准号:
      16H05285
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.07万
    • 财政年份:
      2016
    • 负责人:
      Asahina Yasuhiro
    • 依托单位:
    Innate immunity and treatment response in chronic viral hepatitis
    • 批准号:
      25293169
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.81万
    • 财政年份:
      2013
    • 负责人:
      Asahina Yasuhiro
    • 依托单位:
    海外基金