Analysis of negative regulator of necroptosis

坏死性凋亡负调控因子分析

• 批准号: 16K15423
• 负责人: OSHIMA Shigeru
• 金额: $ 2.16万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16K15423/
• 关键词: オートファジー; ユビキチン; ネクロプトーシス

项目成果

Novel polyubiquitin imaging system, PolyUb-FC, visualized atypical polyubiquitin chain in living cells

新型多聚泛素成像系统 PolyUb-FC，可视化活细胞中的非典型多聚泛素链

• 发表时间: 2018
• 作者: Nibe Y;Matsuda H;Aonuma E;Otsubo K;Maeyashiki C;Kobayashi M;Matsuzawa Y;Nakada S;Watanabe M;and Oshima S
• 通讯作者: and Oshima S

Necroptosis stimulation regulates SQSTM1/p62-LC3 complex formation and polyubiquitination

坏死性凋亡刺激调节 SQSTM1/p62-LC3 复合物形成和多泛素化

• 发表时间: 2018
• 作者: Emi Aonuma;Yoichi Nibe;Hiroki Matsuda;Kana Otsubo;Chiaki Maeyashiki;Masanori Kobayashi;Yu Matsuzawa;Mamoru Watanabe;Shigeru Oshima
• 通讯作者: Shigeru Oshima

HADHA, the alpha subunit of the mitochondrial trifunctional protein, is involved in long-chain fatty acid-induced autophagy in intestinal epithelial cells

• DOI: 10.1016/j.bbrc.2017.01.159
• 发表时间: 2017-03-11
• 期刊: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
• 影响因子: 3.1
• 作者: Maeyashiki, Chiaki;Oshima, Shigeru;Watanabe, Mamoru
• 通讯作者: Watanabe, Mamoru

Indentification of autophagic regulators as therapeutic targets in intestinal epithelial cells.

鉴定自噬调节因子作为肠上皮细胞的治疗靶点。

• 发表时间: 2016
• 作者: Chiaki Maeyashiki;Shigeru Oshima;Yoishi Nibe;Masanori Kobayashi;Mamoru Watanabe.
• 通讯作者: Mamoru Watanabe.

Novel polyubiquitin imaging reveals that atypical polyubiquitin contribute to autophagy

新型多聚泛素成像揭示非典型多聚泛素有助于自噬

• 发表时间: 2017
• 作者: Nibe Y;Oshima S;Aonuma E;Matsuda H;Otsubo K;Maeyashiki C;Kobayashia M;Matsuzawa Y ;Nakada S;Watanabe M.
• 通讯作者: Watanabe M.