Multiple Quantum Coherence NMR and its Application to Molecular Structure Study.

多量子相干核磁共振及其在分子结构研究中的应用。

• 批准号: 60840010
• 负责人: HIKICHI Kunio
• 金额: $ 4.99万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research
• 财政年份: 1985
• 资助国家: 日本
• 起止时间: 1985 至 1986
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-60840010/
• 关键词: Nuclear Magnetic Resonance; Double Quantum Coherence; 2D-NMR; INADEQUATE; DECSY; NMR; 多量子コヒーレンス; 2次元

We developed the NMR method utilizing the multiple quantum coherence and applied it to the study of molecular structure. The multiple-relay correlation spectroscopy in which the single quantum coherence of a spin is transferred to other spins far apart four bonds was developed. This method was applied to cellooligosaccharides. It was found that this method is quite useful to separate out each single saccharide unit. Double quantum coherence echo correlated spectroscopy(DECSY) was developed. This method of 1H was applied to poly(vinyl alcohol) to determine equivalent methylene protons in the sequence of different stereoregularity. The <^(13)C> version of this method was also applied to the determination of stereoregularity of polypropylene oxide and the identification of cis and trans units of polybutadiene. Multiple quantum filter was utilized to separate out the two-spin system. Pure phase COSY became possible with double quantum filter. COSY with triple quantum filter was applied to poly (vinyl alcohol) to determine equivalent methylene protons.

我们开发了利用多量子相干性的核磁共振方法，并将其应用于分子结构的研究。开发了多中继相关光谱，其中自旋的单量子相干性转移到远离四个键的其他自旋。该方法适用于纤维寡糖。人们发现该方法对于分离单个糖单元非常有用。开发出双量子相干回波相关光谱（DECSY）。该 1H 方法应用于聚（乙烯醇），以确定不同立构规整性序列中的等效亚甲基质子。该方法的<^(13)C>版本还应用于聚环氧丙烷立构规整性的测定以及聚丁二烯的顺式和反式单元的鉴定。利用多量子滤波器分离出双自旋系统。双量子滤光片使纯相 COSY 成为可能。将带有三量子滤光片的 COSY 应用于聚（乙烯醇）以确定当量亚甲基质子。

项目成果

Kunio Hikichi: "Two-Dimensional <^1H> and <^(13)C> Nuclear Magnetic Resonance Studies of Poly(vinyl alcohol)" Polymer Journal. in press.

Kunio Hikichi：“聚乙烯醇的二维<^1H>和<^(13)C>核磁共振研究”聚合物杂志。

Mitsuhiko Ikura: Carbohydrate Research.

井仓光彦：碳水化合物研究。

引地邦男: 化学総説. 49. 13-25 (1986)

Kunio Hikichi：化学评论。49。13-25（1986）

Mitsuhiko Ikura: "Two-Dimensional " H-n.m.r. studies of Cellooligosaccharides: The Utility of Multiple-Relay Chemical Shift Correlated Spectroscopy" Carbohydrate Research. in press.

井仓光彦：“二维”H-n.m.r.

引地邦男: 月刊フィジクス. 6. 636-641 (1985)

邦男彦吉：《物理学月刊》。6. 636-641 (1985)