Study of the measurement of halitosis by thin film semi-conductor sensor

薄膜半导体传感器测量口臭的研究

• 批准号: 63870083
• 负责人: SHIMADA Yoshihiro
• 金额: $ 7.49万
• 依托单位: TOHOKU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-63870083/
• 关键词: Halitosis; Volatile Sulfur Compound; Thin Film Sensor; Measurement; Mouth Air Chamber; 半導体薄膜センサ; 口臭測定器

The present time, in general dental clinic, the judgment of halitosis of the patients who complaining bad breath is due to the olfactory sense of dentists. But the olfactory sense of panelists is changed by their physical condition or aging. For avoiding these troubles, the panelists must be tested of their olfactory sense by standard method and plural panelists are needed. Because of these many limitations, reliable analytical method was expected.We reported that the concentration of volatile sulfur compounds(VSC) analyzed by gas chromatography is well correspond to the judgement of halitosis by panel. But in general dental clinic, it is very hard to prepare the gas chromatography, for needed special techniques and high cost. So, the development of convenient olfactometer was expected.We aimed to develop a convenient olfactometer composed of thin film zinc oxide semi-conductor sensor which is high selective to VSC. We made the first and the second trial olfactometer and tested their e … More fficiency. The result are as follows. The sensitivity of this sensor is sufficient to detect noticeable halitosis revel of VSC. The sensitivity revel of acetone and ethylalcohol, the typical organic contents in mouth air, are 1/10 fold lower than VSC which shows good selectivity of this sensor. Repeating measuring test to standard halitosis air is sufficient reproducibility.The selectivity is improved by using acidic absorbent filter. A mouth air chamber which accumulate a certain volume of mouth air, is useful to decreasing the detective variance and is also useful to protect the contamination of saliva into the detective path.The practice measuring was done to mouths, using this olfactometer, and the time for preheat is about 3 minutes, measuring time is one and half minutes and about 3 minutes is necessary for the next measuring. But repeating measurements to same person with passage time showed considerable variance. Further study is necessary whether this variance was caused by the changes of mouth odor with passage of time or whether by the sampling methods of mouth air. Less

目前，在一般的牙科诊所，对抱怨口臭的患者的口臭的判断是由于牙医的嗅觉。但小组成员的嗅觉会因他们的身体状况或年龄而改变。为了避免这些麻烦，必须用标准的方法对小组成员进行嗅觉测试，并且需要多个小组成员。由于存在诸多的局限性，需要一种可靠的分析方法。我们报道了气相色谱法分析的挥发性硫化合物（VSC）浓度与面板对口臭的判断相吻合。但在一般牙科诊所，气相色谱法的制备非常困难，需要特殊的技术，成本也很高。因此，人们期待着开发一种方便的嗅觉测试仪。我们的目标是研制一种方便的、对VSC具有高选择性的薄膜氧化锌半导体传感器。我们做了第一个和第二个试用嗅觉仪，并测试了它们的效率。结果如下。该传感器的灵敏度足以检测到明显的VSC口臭水平。对口腔空气中典型有机物丙酮和乙醇的灵敏度比VSC低1/10，表明该传感器具有良好的选择性。对标准口臭空气的重复测量试验具有足够的再现性。采用酸性吸附过滤器，提高了选择性。口腔空气室积聚一定体积的口腔空气，有助于减少检测方差，也有助于防止唾液污染到检测路径。使用该嗅觉计对口腔进行了练习测量，预热时间约为3分钟，测量时间为1分半钟，下一次测量需要约3分钟。但随着时间的推移，对同一个人重复测量显示出相当大的差异。这种差异是由口腔气味随时间的变化引起的，还是由口腔空气的采样方法引起的，还需要进一步研究。少

项目成果

Yoko YASUNO, Masaki IWAKURA, Yoshihiro SHIMADA, Sai SAKAI: "Study on the Estimation of Halitosis by the Thin Film Semiconductor Sensor" Journal of Dental Health. 39(4). 606-607 (1989)

Yoko YASUNO、Masaki IWAKURA、Yoshihiro Shimada、Sai SAKAI：“薄膜半导体传感器估计口臭的研究”牙科健康杂志。

安野陽子、岩倉政城、島田義弘、酒井才: "半導体薄膜センサを用いて口臭測定法の検討" 口腔衛生学会雑誌. 39. 606-607 (1989)

Yoko Yasuno、Masaki Iwakura、Yoshihiro Shimada、Sai Sakai：“使用半导体薄膜传感器的口臭测量方法的研究”口腔卫生学会杂志 39. 606-607 (1989)。

安野陽子,岩倉政城,島田義弘,酒井才: "半導体薄膜センサを用いた口臭測定法の検討" 口腔衛生学会雑誌. 39. 606-607 (1989)

Yoko Yasuno、Masashiro Iwakura、Yoshihiro Shimada、Sai Sakai：“使用半导体薄膜传感器的口臭测量方法的研究”口腔卫生学会杂志 39. 606-607 (1989)。