The research of targeting tumor-associated macrophages, a new combination therapy strategy by macrophage polarization and immune checkpoint blockade

靶向肿瘤相关巨噬细胞的研究,巨噬细胞极化与免疫检查点阻断的联合治疗新策略

基本信息

  • 批准号:
    21K15586
  • 负责人:
  • 金额:
    $ 2.91万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
  • 财政年份:
    2021
  • 资助国家:
    日本
  • 起止时间:
    2021-04-01 至 2023-03-31
  • 项目状态:
    已结题

项目摘要

项目成果

期刊论文数量(7)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Combined phospholipids adjuvant augments anti-tumor immune responses through activated tumor-associated dendritic cells.
  • DOI:
    10.1016/j.neo.2023.100893
  • 发表时间:
    2023-05
  • 期刊:
  • 影响因子:
    4.8
  • 作者:
    Shui, Yifang;Hu, Xin;Hirano, Hiroshi;Tsukamoto, Hirotake;Guo, Wen-Zhi;Hasumif, Kenichiro;Ijima, Fumihiro;Fujino, Masayuki;Li, Xiao-Kang
  • 通讯作者:
    Li, Xiao-Kang
Enhancement of antitumor effects of PD-L1 blockade by 5-ALA/SFC via upregulation of exhausted T cells metabolism in mice
5-ALA/SFC 通过上调小鼠耗竭 T 细胞代谢增强 PD-L1 阻断的抗肿瘤作用
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Xin Hu;Hiroshi Hirano;Kenichiro Hasumi;Motowo Nakajima;Xiao-Kang Li.
  • 通讯作者:
    Xiao-Kang Li.
β-glucan from Aureobasidium pullulans augments the anti-tumor immune responses through activated tumor-associated dendritic cells
来自出芽短梗霉的 β-葡聚糖通过激活肿瘤相关树突状细胞增强抗肿瘤免疫反应
  • DOI:
    10.1016/j.intimp.2021.108265
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    5.6
  • 作者:
    Shui Yifang;Hu Xin;Hirano Hiroshi;Kusano Kisato;Tsukamoto Hirotake;Li Mengquan;Hasumi Kenichiro;Guo Wen-Zhi;Li Xiao-Kang
  • 通讯作者:
    Li Xiao-Kang
Liver mononuclear cells-derived NK cells for treatment of hepatocellular carcinoma
肝单核细胞衍生的 NK 细胞用于治疗肝细胞癌
  • DOI:
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Xin Hu;Masayuki Fujino;Xiao-Kang Li
  • 通讯作者:
    Xiao-Kang Li
PD-L1 antibody enhanced the β-glucan antitumor effects via blockade the immune checkpoints in melanoma model
PD-L1抗体通过阻断黑色素瘤模型中的免疫检查点增强β-葡聚糖的抗肿瘤作用
  • DOI:
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Xin Hu;Hiroshi Hirano;Masayuki Fujino;Xiao-Kang Li
  • 通讯作者:
    Xiao-Kang Li
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Hu Xin其他文献

Realization of a flat-response photocathode for x-ray streak cameras
用于 X 射线条纹相机的平坦响应光电阴极的实现
  • DOI:
    10.1364/oe.23.019793
  • 发表时间:
    2015
  • 期刊:
  • 影响因子:
    3.8
  • 作者:
    Wang Chuanke;Li Jin;Hu Xin;Hu Zhimin;Zhu Xiaoli;Deng Bo;Yi Tao;Fan Quanping;Cao Zhurong;Liu Shenye;Jiang Shaoen;Ding Yongkun;Xie Changqing;Jiang Gang
  • 通讯作者:
    Jiang Gang
Effects of wet and dry ball milling on the physicochemical properties of sawdust derived-biochar
湿法和干法球磨对木屑生物炭理化性质的影响
Determination of inorganic elements in rat serum, and vegetable and fruit ferment liquid by ICP-MS
ICP-MS测定大鼠血清和蔬菜水果发酵液中的无机元素
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Chen Yi-jun;Cai Yun-qing;Lu Ming;Mao Li;Li Xiang-yun;Hu Xin;Lian Hong-zhen
  • 通讯作者:
    Lian Hong-zhen
Secrecy Energy Efficiency in Wireless Powered Heterogeneous Networks: A Distributed ADMM Approach
无线供电异构网络中的保密能源效率:分布式 ADMM 方法
  • DOI:
    10.1109/access.2018.2825387
  • 发表时间:
    2018-04
  • 期刊:
  • 影响因子:
    3.9
  • 作者:
    Hu Xin;Li Bin;Huang Kaizhi;Fei Zesong;Wong Kai Kit
  • 通讯作者:
    Wong Kai Kit
The resolvent of the linearized Boltzmann operator with a stationary potential
具有平稳势的线性化玻尔兹曼算子的求解

Hu Xin的其他文献

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{{ truncateString('Hu Xin', 18)}}的其他基金

The research of targeting tumor-associated dendritic cells, a new therapy strategy by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses
靶向肿瘤相关树突状细胞的研究,树突状细胞介导肿瘤相关抗原的摄取和抗肿瘤反应的新治疗策略
  • 批准号:
    23K14668
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists

相似海外基金

Nucleic acid stimulation-induced mechanism to overcome MDSC-mediated immune tolerance in tumor microenvironment
核酸刺激诱导机制克服肿瘤微环境中MDSC介导的免疫耐受
  • 批准号:
    24K18539
  • 财政年份:
    2024
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
Elucidation of Tumor Microenvironment Network Regulated by Fibrinolysis Inhibitory Factor and Its Therapeutic Application
纤溶抑制因子调控的肿瘤微环境网络的阐明及其治疗应用
  • 批准号:
    23K06612
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Role of the circadian rhythm in the regulation of the tumor microenvironment of non-small cell cancer
昼夜节律在非小细胞癌肿瘤微环境调节中的作用
  • 批准号:
    478693
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Operating Grants
Targeting protein arginine methylation in the 9p21.3 loss tumor microenvironment
9p21.3 缺失肿瘤微环境中的靶向蛋白精氨酸甲基化
  • 批准号:
    489995
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Operating Grants
Elucidating mechanism of fibrinogen elevation induced by immuno tumor microenvironment
阐明免疫肿瘤微环境诱导纤维蛋白原升高的机制
  • 批准号:
    23K15504
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
Genomic abnormalities in the tumor microenvironment and clonal hematopoiesis
肿瘤微环境和克隆造血的基因组异常
  • 批准号:
    23KK0149
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Fund for the Promotion of Joint International Research (International Collaborative Research)
Understanding MMP3-rich exosomes on neoplastic cell communication in tumor microenvironment
了解富含 MMP3 的外泌体对肿瘤微环境中肿瘤细胞通讯的影响
  • 批准号:
    22KF0268
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for JSPS Fellows
High resolution profiling of cellular communities in the tumor microenvironment
肿瘤微环境中细胞群落的高分辨率分析
  • 批准号:
    10572355
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
Targeting tumor microenvironment by nanoimmunodrugs for glioma treatment
纳米免疫药物靶向肿瘤微环境治疗神经胶质瘤
  • 批准号:
    10743942
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
Tumor microenvironment in colorectal cancer and exploration for therapeutic target
结直肠癌的肿瘤微环境及治疗靶点探索
  • 批准号:
    23K08161
  • 财政年份:
    2023
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
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