Establishing New Therapeutic Strategy for Urothelial Carcinoma

建立尿路上皮癌的新治疗策略

• 批准号: 21K16757
• 负责人: Ogihara Koichiro
• 金额: $ 2.91万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2021
• 资助国家: 日本
• 起止时间: 2021-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21K16757/
• 关键词: 尿路上皮癌; IDH2阻害薬; 抗癌剤耐性; シスチントランスポーター; CDDP; GSSG/GSH; 癌幹細胞仮説; 筋層非浸潤性膀胱癌; 代謝リプログラミング; CD44v; メタボローム解析; RNA sequence

项目成果

Role of Previous Malignancy History in Clinical Outcomes in Patients with Initially Diagnosed Non-Muscle Invasive Bladder Cancer

• DOI: 10.1245/s10434-021-09750-0
• 发表时间: 2021-03-05
• 期刊: ANNALS OF SURGICAL ONCOLOGY
• 影响因子: 3.7
• 作者: Kufukihara, Ryohei;Kikuchi, Eiji;Oya, Mototsugu
• 通讯作者: Oya, Mototsugu

Guideline adherence for radical cystectomy significantly affects survival outcomes in non-muscle-invasive bladder cancer patients

根治性膀胱切除术指南的遵守显着影响非肌层浸润性膀胱癌患者的生存结果

• DOI: 10.1093/jjco/hyab060
• 发表时间: 2021
• 期刊: Japanese Journal of Clinical Oncology
• 影响因子: 2.4
• 作者: Kayama Emina;Shigeta Keisuke;Kikuchi Eiji;Ogihara Koichiro;Hakozaki Kyohei;Iwasawa Tomohiro;Kamisawa Ken;Kanai Kunimitsu;Ide Hiroki;Hara Satoshi;Mizuno Ryuichi;Oya Mototsugu
• 通讯作者: Oya Mototsugu

ASO Author Reflections: Previous History of Non-urothelial Malignancy May Provide Predictive Information of Worse Clinical Outcome for Initially Diagnosed Non-Muscle Invasive Bladder Cancer

ASO 作者感言：既往非尿路上皮恶性肿瘤病史可能为初步诊断的非肌肉浸润性膀胱癌提供更糟糕临床结果的预测信息

• DOI: 10.1245/s10434-021-09787-1
• 发表时间: 2021
• 期刊: Annals of Surgical Oncology
• 影响因子: 3.7
• 作者: Kufukihara Ryohei;Kikuchi Eiji;Ogihara Koichiro;Shigeta Keisuke;Oya Mototsugu
• 通讯作者: Oya Mototsugu

Diagnostic performance of the vesical imaging-reporting and data system for detecting muscle-invasive bladder cancer in real clinical settings: Comparison with diagnostic cystoscopy

• DOI: 10.1016/j.urolonc.2021.07.005
• 发表时间: 2022-01-29
• 期刊: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
• 影响因子: 2.7
• 作者: Kufukihara, Ryohei;Kikuchi, Eiji;Oya, Mototsugu
• 通讯作者: Oya, Mototsugu

Does neoadjuvant chemotherapy have therapeutic benefit for node-positive upper tract urothelial carcinoma? Results of a multi-center cohort study

• DOI: 10.1016/j.urolonc.2021.07.029
• 发表时间: 2022-02-24
• 期刊: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
• 影响因子: 2.7
• 作者: Shigeta, Keisuke;Matsumoto, Kazuhiro;Oya, Mototsugu
• 通讯作者: Oya, Mototsugu