miRNA-9 delivery using lactosome, a newly-developed drug delivery system, in the treatment of rheumatoid arthritis
miRNA-9 delivery using lactosome, a newly-developed drug delivery system, in the treatment of rheumatoid arthritis
批准号:
22K16341
负责人:
LEE WENSHI
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Early-Career Scientists
财政年份:
2022
资助国家:
日本
项目状态:
已结题
起止时间:
2022-04-01 至 2024-03-31
中文摘要
在胶原诱导的关节炎小鼠模型中静脉注射lactosome-mir 9,并以lactosome-control siRNA作为对照组,miR-9组的平均关节炎评分相对低于对照组。关节的组织学评估目前正在进行中。
英文摘要
We injected lactosome-mir9 intravenously into collagen-induced arthritis mouse model, with lactosome-control siRNA as control group.The mean arthritic score was relatively lower in miR-9 group compared to the control group. The histological assessments for the joints are currently under progress.
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科研奖励(0)
会议论文
The delivery of miR-9 and RasGRP4 siRNA via high selectivity bispecific antibody conjugated lactosome: Targeting therapy for rheumatoid arthritis (RA) active synovial macrophage and osteoclast
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批准号:24K19237
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项目类别:Grant-in-Aid for Early-Career Scientists
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资助金额:$3.0万
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财政年份:2024
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负责人:LEE WENSHI
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依托单位:
国内基金
海外基金
Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis
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批准号:31171277
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项目类别:面上项目
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资助金额:60.0万元
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批准年份:2011
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负责人:Christine Nardini
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依托单位:
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
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批准号:31070748
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项目类别:面上项目
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资助金额:34.0万元
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批准年份:2010
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负责人:Christine Nardini
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依托单位: