The impact of platelets on the maintenance of pancreatic β cell mass and development of diabetes (B10+)
The impact of platelets on the maintenance of pancreatic β cell mass and development of diabetes (B10+)
批准号:
406534138
负责人:
金额:
$0.0万
依托单位国家:
德国
项目类别:
CRC/Transregios
财政年份:
2018
资助国家:
德国
项目状态:
已结题
起止时间:
2017-12-31 至 2021-12-31
中文摘要
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英文摘要
Our preliminary results indicate that platelets promote survival of pancreatic β cells and prevent development of diabetes in mice. We will further investigate the impact of platelets on β cells to unravel specific mechanisms mediating this process. Furthermore, we aim to identify platelet-derived factors directly or indirectly preventing β cell death. Finally, we will attempt to corroborate our data in humans.
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