SFB 1411: Design of particulate products

CRC 1411的长期愿景是颗粒产品的预测性设计，即具有可控大小、形状和组成的颗粒系统。这一目标将通过两步走的方法来实现。首先，建立描述结构-属性函数的预测模型，并使用该模型来优化特定目标函数所需的粒子结构，即期望的产品属性。其次，描述工艺-结构函数的一组预测模型随后确定最佳工艺条件，以制造具有所需结构的颗粒系统。这一挑战由四个相互关联的研究领域(RAS)来解决，它们集中在颗粒形成(RA A)、它们的层析分离(RA B)、综合表征(RA C)以及建模和优化(RA D)。在第一个资助期，CRC1411在颗粒产品的目标预测性设计方面取得了重大进展。这些科学突破是使用行为相对良好的模型系统实现的，例如各向同性颗粒、尺寸排除层析或作为薄膜的颗粒排列的结构优化。在成功地建立了一般方法、基础设施和协作之后，CRC 1411现在可以完美地应对几个步骤的变化。在第二个资助期，我们的目标是继续制造各向异性粒子系统，进行集成处理，并建立强大的相互作用层析方案，承诺增强NP的分离能力。此外，分散性和非理想性在结构形成中的作用将是第二个资助期的核心新动机。通过从根本上了解颗粒积木在不同尺度上的自组织，并通过探索结构不规则性如何影响着色或色谱分离中的功能特性，我们最终将能够缓解此类影响，并设计性能优化的健壮工艺。优越的研究环境包括弗里德里希-亚历山大-纽伦堡大学(FAU)、杜伊斯堡-埃森大学(UDE)的纳米能源技术中心(NETZ)和赫尔姆霍兹可再生能源研究所(HI ERN)的五个跨学科中心，为CRC 1411提供了理想的平台。通过广泛的国际合作伙伴网络和一系列国际会议和研讨会，我们坚定地确立了CRC 1411作为颗粒产品设计的高知名度研究中心的地位。通过现代和跨学科的综合研究培训小组、开创性的数据基础设施、一整套支持两性平等和有利于家庭的工作环境的协调一致的措施，以及一个专门的外联项目，CRC1411积极塑造粒子技术以及FAU和有关研究所的形象。

The long-term vision of CRC 1411 is the predictive design of particulate products, i.e., particle systems with controlled size, shape, and composition. This objective will be achieved by a two-step approach. First, predictive models describing structure-property functions are established and used to optimise the required particle structure for a specific target function, i.e., a desired product property. Second, a set of predictive models describing the process-structure functions subsequently determine optimised process conditions to fabricate particle systems with the desired structure. This challenge is approached by four strongly interlinked research areas (RAs), focussing on particle formation (RA A), their chromatographic separation (RA B), comprehensive characterisation (RA C), and modelling and optimisation (RA D). In the first funding period, CRC 1411 made significant progress towards the targeted predictive design of particulate products. These scientific breakthroughs were realised using comparatively well-behaved model systems, such as isotropic particles, size exclusion chromatography, or structure optimisation of particle arrangements as thin films. Having successfully established general methodologies, infrastructure and collaborations, CRC 1411 is now perfectly set to address several step changes. In the second funding period, we will target the continuous fabrication of anisotropic particle systems, their integrated processing and the establishment of powerful, interaction chromatography schemes, which promises enhanced NP separation capabilities. In addition, the role of dispersities and non-idealities in structure formation will be a central new motive in the second funding period. By fundamentally understanding the selforganisation of particulate building blocks across the scales and by exploring how structural irregularities influence functional properties in colouration or chromatographic separation, we will ultimately be able to mitigate such effects and design robust processes with optimised performance. The excellent research environment including five interdisciplinary centres at the Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), the NanoEnergieTechnikZentrum (NETZ) at the University of Duisburg-Essen (UDE) and the Helmholtz Institute for Renewable Energy (HI ERN) provides the ideal platform for CRC 1411. Evidenced by a broad network of international partners and a set of international conferences and workshops, we have firmly established CRC 1411 as a highly visible research centre for the design of particulate products. With the modern and interdisciplinary integrated research training group, a pioneering data infrastructure, a coherent set of measures supporting gender equality and a family-friendly working environment, and a dedicated out-reach project, CRC 1411 actively shapes particle technology as well as the profile of FAU and the involved institutes.