Cooperative Triazole H-Donors in Asymmetric Dearomatization by Anion-Binding Catalysis (A12#)

阴离子结合催化不对称脱芳构化中的合作三唑 H 供体 (A12

• 批准号: 417602097
• 金额: --
• 依托单位: Organisch-Chemisches Institut
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2018
• 资助国家: 德国
• 起止时间: 2017-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/417602097?language=en
• 关键词: Cooperative; Triazole; Donors; Asymmetric; Dearomatization

In this project, the cooperative binding and reactivity of chiral tetrakis-triazoles (TetraTri) structures as C-H-based neutral anion acceptors in catalytic anion-binding processes will be explored. Thus, the influence and the controllability of self-organized structures, their host-guest complexes (with one or more anions) and the cooperativity nature of the binding will be investigated by physical and analytical methods, complemented by quantum mechanical studies. Finally, novel applications in enantioselective anion-binding organocatalyzed dearomatization process of N- and O-heteroarenes will be developed.

本项目将探讨手性四聚三唑（TetraTri）结构作为c - h基中性阴离子受体在催化阴离子结合过程中的协同结合和反应性。因此，自组织结构的影响和可控性，它们的主客体复合物（具有一个或多个阴离子）和结合的协同性将通过物理和分析方法进行研究，并辅以量子力学研究。最后，将在N-和o -杂芳烃的对映选择性阴离子结合有机催化脱芳过程中开发新的应用。