Blood Pressure and Urinary Bisphenol A Concentrations After Soda Consumption from Cans

喝罐装饮料是非常常见的。烧碱消耗最多的是接触含双酚A的环氧树脂内衬的易拉罐。罐装汽水造成的双酚A(BPA)暴露的负担很大，还没有得到充分的研究。可口可乐的酸度很高，pH为2.5，有利于双酚A从环氧层中浸出。同样，罐装汽水的摄入量可能会因为罐头中的双酚A含量而升高血压。鉴于高血压在人群中的持续增加，这将产生重大影响。因此，我们建议进行一项随机、单盲、交叉干预试验，以评估饮用罐装可口可乐后的尿双酚A浓度，以解决这些重要问题。

Consumption of beverages from cans is extremely common. Soda consumption is the most frequent exposure to Bisphenol A-containing epoxy resin lining of cans. The burden of Bisphenol A (BPA) exposure resulting from canned sodas is significant and has not been sufficiently studied. Coca-cola has a high acidity level with a pH of 2.5 fostering BPA leaching from the epoxy lining. Similarly, canned soda consumption may raise blood pressure due to the BPA content of cans. This would have significant implications given the continuing increase of hypertension in the population. We therefore propose to conduct a randomized single-blind cross-over intervention trial to evaluate urinary BPA concentrations after consuming coca-cola from cans to address these significant questions.