Development a New Biliary Reconstruction Using Antireflux Intestinal Spur Valve
Development a New Biliary Reconstruction Using Antireflux Intestinal Spur Valve
批准号:
01480319
负责人:
OHI Ryoji
金额:
$3.78万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (B)
财政年份:
1989
资助国家:
日本
项目状态:
已结题
起止时间:
1989 至 1990
中文摘要
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英文摘要
We conducted this study to establish the best method for construction of intestinal antireflux spur valve which could be beneficial in prevention of ascending cholangitis in cases treated by hepatic portoenterostomy and similar conditions.Materials and Methods :Fourteen Mongrel dogs of both sexes weighing from 10-20Kg were used, among which 2 dogs served as control. For all dogs, a spur valve was constructed by denuding the seromuscular layer of one side of the distal end of the jejunal conduit and then suturing the boundries of the denuded area to the duodenum. The size of the valves was 2cm in 6 dogs, 5cm in 6 dogs and no valve was constructed in the remaining 2 control dogs. Manometric studies, barium studies and histopathological studies were performed.Results :Results were expressed as poor, fair and good. In control dogs there was no valve action and reflux could be observed easily. In dogs with 2cm sized valve 4 out of 6 showed good results and 2 fair. While in dogs with 5cm sized valve 3 out of 6 were good, 2 poor and 1 fair. Opening pressure in fair and good cases ranged from 11 to 20 cmH20. The efficacy of the valve for anti-reflux mechanism was better in later examinations than in earlier ones and it was due to the initial mild inflammatory process within the valve.
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Chiba, T., Ohi, R. and Mochizuki I.: "Cholangiographic study of the pancreaticobiliary ductal junction in biliary atresia," J. Pediatr. Surg. 25. 609-612 (1990)
Chiba, T.、Ohi, R. 和 Mochizuki I.:“胆道闭锁胰胆管连接处的胆管造影研究”,J. Pediatr。
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大井龍司,他7名: "胆道閉鎖症の治療の現況と問題点-特に手術成結と長期存在例の検討-" 日本外科学会雑誌. 90. 1339-1342 (1989)
Ryuji Oi 等 7 人:“胆道闭锁治疗的现状和问题 - 特别是手术结果和长期病例的检查 -” 日本外科学会杂志 90. 1339-1342 (1989)。
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大井 龍司: "胆道閉領症治寮の変〓と今後の動向" 肝胆〓. 19. 594-599 (1989)
Ryuji Oi:“胆道闭锁治疗的变化和未来趋势”《Liver and Biblio》19. 594-599 (1989)。
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大井 龍司: "胆道閉鎖症治療の変遷と今後の動向" 肝胆膵. 19. 594-599 (1989)
Ryuji Oi:“胆道闭锁治疗的变化和未来趋势”《肝胆胰》19. 594-599 (1989)。
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千葉 庸夫他4名: "胆道閉鎖症の晩期合併症とその背景因子に関する臨床的検討" 日小外会誌. 26. 786-790 (1990)
Tsuneo Chiba 等 4 人:“胆道闭锁晚期并发症及其背景因素的临床研究”日本外国学会杂志 26. 786-790 (1990)。
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共 23 条
Attempt of producing an experimental animal model of biliary atresia using bcl-2 knock-out mice : the analysis of bcl-2 as the apoptosis inhibitor in biliary atresia
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批准号:11557129
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.13万
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财政年份:1999
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负责人:OHI Ryoji
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依托单位:
胎児外科手技を用いた胆道閉鎖症モデル(肝外胆管および肝)作成による病態解明の試み
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批准号:06454502
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.67万
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财政年份:1994
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负责人:OHI Ryoji
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依托单位:
Molecular Biological Studies on Pathogenesis of Biliary Atresia Using PCR method
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批准号:03454311
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.58万
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财政年份:1991
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负责人:OHI Ryoji
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依托单位: